Barcelona Alzheimer Treatment & Research Center

Artículo para la Categoría 2010

Activation of PKR Causes Amyloid ß-Peptide Accumulation Via De-Repression of BACE1 Expression.

Activation of PKR Causes Amyloid ß-Peptide Accumulation Via De-Repression of BACE1 Expression. Ill-Raga G, Palomer E, Wozniak MA, Ramos-Fernández E, Bosch-Morató M, Tajes M, Guix FX, Galán JJ, Clarimón J, Antúnez C, Real LM, Boada M, Itzhaki RF, Fandos C, Muñoz FJ. PLoS One. 2011;6(6):e21456. PDF

Estrogen receptor alpha gene variants are associated with Alzheimer’s disease.

Estrogen receptor alpha gene variants are associated with Alzheimer’s disease. Boada M, Antunez C, López-Arrieta J, Caruz A, Moreno-Rey C, Ramírez-Lorca R, Morón FJ, Hernández I, Mauleón A, Rosende-Roca M, Martínez-Lage P, Marín J, Tárraga L, Alegret M, Pedrajas JR, Urda N, Royo JL, Saez ME, Gayán J, González-Pérez A, Real LM, Ruiz A,

Matrix metalloproteinase 2 (MMP-2) degrades soluble vasculotropic amyloid-beta E22Q and L34V mutants, delaying their toxicity for human brain microvascular endothelial cells.

Matrix metalloproteinase 2 (MMP-2) degrades soluble vasculotropic amyloid-beta E22Q and L34V mutants, delaying their toxicity for human brain microvascular endothelial cells. Hernandez-Guillamon M, Mawhirt S, Fossati S, Blais S, Pares M, Penalba A, Boada M, Couraud PO, Neubert TA, Montaner J, Ghiso J, Rostagno A. J Biol Chem. 2010 Aug

Regional variation on the presentation of AD patients in memory clinics within Europe – data from the ICTUS study.

Regional variation on the presentation of AD patients in memory clinics within Europe – data from the ICTUS study. Hausner L, Frölich L., Gardette V, Reynish E, Ousset PJ, Andrieu S2), Vellas B, on behalf of theICTUS-EADC study group. J Alzheimers Dis. 2010 Jan;21(1):155-65.

Brain perfusion correlates of visuoperceptual deficits in preclinical and mild Alzheimer disease.

Brain perfusion correlates of visuoperceptual deficits in preclinical and mild Alzheimer disease. Alegret M, Vinyes-Junqué G, Boada M, Martínez-Lage P, Cuberas G, Espinosa A, Roca I, Hernández I, Valero S,Rosende-Roca M, Mauleón A, Becker JT, Tárraga L.  J Alzheimers Dis 21 (2010) 557-567.

Albúmina en la plasmaféresis: una nueva terapia de movilización del beta amiloide en la enfermedad de Alzheimer.

Albúmina en la plasmaféresis: una nueva terapia de movilización del beta amiloide en la enfermedad de Alzheimer. Boada M.  Rev Neurol 2010;50 (Supl. 5):S9-S18] Free full text

Willingness-to-pay for reductions in care need: estimating the value of informal care in Alzheimer’s disease.

Willingness-to-pay for reductions in care need: estimating the value of informal care in Alzheimer’s disease. Gustavsson A, Jönsson L, McShane R, Boada M, Wimo A, Zbrozek AS. Int J Geriatr Psychiatry2010;25:622-632.

Genome-wide Analysis of Genetic Loci Associated With Alzheimer’s Disease.

Genome-wide Analysis of Genetic Loci Associated With Alzheimer’s Disease.Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT Jr, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund

CALHM1 P86L polymorphism is associated to late-onset Alzheimer’s disease in a recessive model.

CALHM1 P86L polymorphism is associated to late-onset Alzheimer’s disease in a recessive model. Boada M, Antúnez C, López-Arrieta J, Galán JJ, Morón FJ, Hernández I, Marín J, Martínez-Lage P, Alegret M, Carrasco JM, Moreno C, Real LM, González-Pérez A, Tárraga L, Ruiz A. J Alzheimers Dis. 2010 Apr;20(1):247-51.

Diagnóstico y evolución de la degeneración lobular fronto-temporal en una unidad de demencias: 12 años de experiencia.

Diagnóstico y evolución de la degeneración lobular fronto-temporal en una unidad de demencias: 12 años de experiencia. Hernández I, Martínez-Lage P, Valero S, Alegret M, Rey MJ, Espinosa A, Mauleón A, Viñas G, Rosende-Roca M, Tárraga L, Boada M.  Alzheimer Real Invest Demenc 2010;44:5-14. PDF

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