Albert Lleó Bisa
I am the director of a Memory Disorders Unit at Hospital de Sant Pau and I have both clinical and research experience in neurodegenerative diseases. My main strength is that as a clinician I see patients regularly and this allows me to face the complexities and challenges of neurodegenerative diseases. In addition to my clinical background I have been conducting translational research since the end of my residency in 2000, and this experience has given me the tools to tackle the most clinically relevant problems in neurodegenerative disease research. This competence has been demonstrated in high impact publications in Nature Medicine, Nat Rev Neurology, JAMA Neurology, Brain and Acta Neuropathologica among many others.
My main lines of research are the molecular basis of neurodegenerative diseases and biomarkers. These lines have yielded a patent and many publications in prestigious journals. Currently, we are pursuing clinical application for such markers and we hope that they will have a role in improving early diagnosis or prognosis. Our research in biomarkers is complemented by our research in digital neuropathology. In particular, we have set-up a combination of superresolution microscopy techniques that we have applied to the study of human brain. Using these unique tools we have described the presence of synaptic aggregates in dementia with Lewy bodies or the detailed composition of human amyloid plaques.