Total impact factor: 67,03
Estrogen receptor alpha gene variants are associated with Alzheimer’s disease
Boada M, Antunez C, López-Arrieta J, Caruz A, Moreno-Rey C, Ramírez-Lorca R, Morón FJ, Hernández I, Mauleón A, Rosende-Roca M, Martínez-Lage P, Marín J, Tárraga L, Alegret M, Pedrajas JR, Urda N, Royo JL, Saez ME, Gayán J, González-Pérez A, Real LM, Ruiz A, Galán JJ.
CALHM86L Polymorphism is a Genetic Modifier of Age at Onset in Alzheimer’s disease : A Meta-Analysis Study
Lambert JC, Sleegers K, González-Pérez A, Ingelsson M, Beecham GW, Hiltunen M, Combarros O, Bullido MJ, Brouwers N, Bettens K, Berr C, Pasquier F, Richard F, Dekosky ST, Hannequin D, Haines JL, Tognoni G, Fiévet N, Dartigues JF, Tzourio C, Engelborghs S, Arosio B, Coto E, De Deyn P, Del Zompo M, Mateo I, Boada M, Antunez C, Lopez-Arrieta J, Epelbaum J, Schjeide BM, Frank-Garcia A, Giedraitis V, Helisalmi S, Porcellini E, Pilotto A, Forti P, Ferri R, Delepine M, Zelenika D, Lathrop M, Scarpini E, Siciliano G, Solfrizzi V, Sorbi S, Spalletta G, Ravaglia G, Valdivieso F, Vepsäläinen S, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Hanon O, Piccardi P, Annoni G, Mann D, Marambaud P, Seripa D, Galimberti D, Tanzi RE, Bertram L, Lendon C, Lannfelt L, Licastro F, Campion D, Pericak-Vance MA, Soininen H, Van Broeckhoven C, Alpérovitch A, Ruiz A, Kamboh MI, Amouyel P. J Alzheimers Dis
Matrix metalloproteinase 2 (MMP-2) degrades soluble vasculotropic amyloid-beta E22Q and L34V mutants, delaying their toxicity for human brain microvascular endothelial cells
Hernandez-Guillamon M, Mawhirt S, Fossati S, Blais S, Pares M, Penalba A, Boada M, Couraud PO, Neubert TA, Montaner J, Ghiso J, Rostagno A.
Regional variation on the presentation of AD patients in memory clinics within Europe – data from the ICTUS study
Hausner L, Frölich L., Gardette V, Reynish E, Ousset PJ, Andrieu S2), Vellas B, on behalf of the ICTUS-EADC study group.
Albúmina en la plasmaféresis: una nueva terapia de movilización del beta amiloide en la enfermedad de Alzheimer
Boada M.
Willingness-to-pay for reductions in care need: estimating the value of informal care in Alzheimer’s disease
Gustavsson A, Jönsson L, McShane R, Boada M, Wimo A, Zbrozek AS.
Genome-wide Analysis of Genetic Loci Associated With Alzheimer’s Disease
Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT Jr, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM, Breteler MM; CHARGE Consortium; GERAD1 Consortium; EADI1 Consortium.
CALHM1 P86L polymorphism is associated to late-onset Alzheimer’s disease in a recessive model
Boada M, Antúnez C, López-Arrieta J, Galán JJ, Morón FJ, Hernández I, Marín J, Martínez-Lage P, Alegret M, Carrasco JM, Moreno C, Real LM, González-Pérez A, Tárraga L, Ruiz A.
Genetic screening of Alzheimer’s disease genes in Iberian and African samples yields novel mutations in presenilins and APP
Guerreiro RJ, Baquero M, Blesa R, Boada M, Brás JM, Bullido MJ, Calado A, Crook R, Ferreira C, Frank A, Gómez-Isla T, Hernández I, Lleó A, Machado A, Martínez-Lage P, Masdeu J, Molina-Porcel L, Molinuevo JL, Pastor P, Pérez-Tur J, Relvas R, Oliveira CR, Ribeiro MH, Rogaeva E, Sa A, Samaranch L, Sánchez-Valle R, Santana I, Tárraga L, Valdivieso F, Singleton A, Hardy J, Clarimón
Brain perfusion correlates of visuoperceptual deficits in preclinical and mild Alzheimer disease
J Alzheimers Dis 21 (2010) 557-567. I.F. 4,26
Alegret M, Vinyes-Junqué G, Boada M, Martínez-Lage P, Cuberas G, Espinosa A, Roca I, Hernández I, Valero S, Rosende-Roca M, Mauleón A, Becker JT, Tárraga L.
Diagnóstico y evolución de la degeneración lobular fronto-temporal en una unidad de demencias: 12 años de experiencia
Alzheimer Real Invest Demenc 2010;44:5-14.
Hernández I, Martínez-Lage P, Valero S, Alegret M, Rey MJ, Espinosa A, Mauleón A, Viñas G, Rosende-Roca M, Tárraga L, Boada M.
Total impact factor: 118,89
Tsallis entropy approach to radiotherapy treatments
Physica A: Statistical Mechanics and its Applications, Volume 392, Issue 9, 1 May 2013, Pages 2007-2015, ISSN 0378-4371, I.F. 1,676
Rodriguez-Perez D, Sotolongo-Costa O, Antoranz JC.
ATP5H/KCTD2 locus is associated with Alzheimer's disease risk
Mol Psychiatry. 2014 Jun; I.F. 14,9 doi:19(6):682-7.
Boada M, Antúnez C, Ramírez-Lorca R, Destefano AL, González-Pérez A, Gayán J, López-Arrieta J, Ikram MA, Hernández I, Marín J, Galán JJ, Bis JC, Mauleón A, Rosende-Roca M, Moreno-Rey C, Gudnasson V, Morón FJ, Velasco J, Carrasco JM, Alegret M, Espinosa A, Vinyes G, Lafuente A, Vargas L, Fitzpatrick AL; for the Alzheimer’s Disease Neuroimaging Initiative, Launer LJ, Sáez ME, Vázquez E, Becker JT, López OL, Serrano-Ríos M, Tárraga L, van Duijn CM, Real LM, Seshadri S, Ruiz A.
Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation
Suárez-Calvet M, Dols-Icardo O, Lladó A, Sánchez-Valle R, Hernández I, Amer G, Antón-Aguirre S, Alcolea D, Fortea J, Ferrer I, van der Zee J, Dillen L, Van Broeckhoven C, Molinuevo JL, Blesa R, Clarimón J, Lleó A.
Design of a comprehensive Alzheimer's disease clinic and research center in Spain to meet critical patient and family needs
Alzheimers Dement. 2014 May; I.F. 4,48 doi:10(3):409-15.
Boada M, Tárraga L, Hernández I, Valero S, Alegret M, Ruiz A, Lopez OL, Becker JT; Fundació ACE Alzheimer Research Center and Memory Clinic.
Characterization of the repeat expansion size in C9orf72 in amyotrophic lateral sclerosis and frontotemporal dementia
Hum Mol Genet. 2014 Feb I.F. 7,69 doi:1;23(3):749-54.
Dols-Icardo O, García-Redondo A, Rojas-García R, Sánchez-Valle R, Noguera A, Gómez-Tortosa E, Pastor P, Hernández I, Esteban-Pérez J, Suárez-Calvet M, Antón-Aguirre S, Amer G, Ortega-Cubero S, Blesa R, Fortea J, Alcolea D, Capdevila A, Antonell A, Lladó A, Muñoz-Blanco JL, Mora JS, Galán-Dávila L, Rodríguez De Rivera FJ, Lleó A, Clarimón J.
Assessing the Role of the Trem2 P.R47h Variant as a Risk Factor for Alzheimer's Disease and Frontotemporal Dementia
Neurobiol Aging. 2014 Feb; I.F. 4.85 doi:35(2):444.e1-4.
Ruiz A, Dols-Icardo O, Bullido MJ, Pastor P, Rodríguez-Rodríguez E, López de Munain A, de Pancorbo MM, Pérez-Tur J, Alvarez V, Antonell A, López-Arrieta J, Hernández I, Tárraga L, Boada M, Lleó A, Blesa R, Frank-García A, Sastre I, Razquin C, Ortega-Cubero S, Lorenzo E, Sánchez-Juan P, Combarros O, Moreno F, Gorostidi A, Elcoroaristizabal X, Baquero M, Coto E, Sánchez-Valle R, Clarimón J; dementia genetic Spanish consortium (DEGESCO).
Identification of Misdiagnosed Fronto-Temporal Dementia using APOE Genotype and Phenotype-Genotype Correlation Analyses
Curr Alzheimer Res. 2014 Feb; I.F. 3,68 doi:11(2):182-91
Hernández I, Mauleón A, Rosende-Roca M, Alegret M, Vinyes G, Espinosa A, Sotolongo-Grau O, Becker JT, Valero S, Tárraga L, López OL, Ruiz A, Boada M.
Genetic analysis of candidate SNPs for metabolic syndrome in obstructive sleep apnea (OSA)
Gene. 2013 May 25; I.F. 2.2 doi:521(1):150-4.
Grilo A, Ruiz-Granados ES, Moreno-Rey C, Rivera JM, Ruiz A, Real LM, Sáez ME.
Cut-off Scores of a brief Neuropsychological Battery (NBACE) for Spanish Individual adults older than 44 years old
PLoS One. 2013 Oct I.F. 3.73 doi:16;8(10):e76436.
Alegret M, Espinosa A, Valero S, Vinyes-Junqué G, Ruiz A, Hernández I, Rosende-Roca M, Mauleón A, Becker JT, Tárraga L, Boada M.
Meta-analysis of 74,538 individuals identifies 11 new susceptibility loci for Alzheimer’s disease
Nat Genet. 2013 Dec; I.F. 35.209 doi:45(12):1452-8.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Hollingworth P, Ramirez A, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer's Disease (GERAD); Alzheimer's Disease Genetic Consortium (ADGC); Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P.
Blood amyloid beta levels in healthy, Mild Cognitive Impairment and Alzheimer's disease individuals: replication of diastolic blood pressure correlations and analysis of critical covariates
Agustín Ruiz, Pedro Pesini, Ana Espinosa, Virginia Pérez-Grijalba, Sergi Valero, Oscar Sotolongo-Grau, Montserrat Alegret, Inmaculada Monleón, Asunción Lafuente, Mar Buendía, Marta Ibarria, Susana Ruiz; Isabel Hernández; Itziar San José, Lluís Tárraga, Mercè Boada, Manuel Sarasa.
Rare variants in Calcium homeostasis modulator 1 (CALHM1) gene found in early onset Alzheimer's disease patients alter calcium homeostasis
Rubio-Moscardo F, Setó-Salvia N, Pera M, Bosch-Morató M, Plata C, Belbin O, Gené G, Dols-Icardo O, Ingelsson M, Helisalmi S, Soininen H, Hiltunen M, Giedraitis V, Lannfelt L, Frank A, Bullido MJ, Combarros O, Sánchez-Juan P, Boada M, Tárraga L, Pastor P, Pérez-Tur J, Baquero M, Molinuevo JL, Sánchez-Valle R, Fuentes-Prior P, Fortea J, Blesa R, Muñoz FJ, Lleó A, Valverde MA, Clarimón J.
Single-Domain Amnestic Mild Cognitive Impairment Identified by Cluster Analysis Predicts Alzheimer's Disease in the European Prospective DESCRIPA Study
Damian M, Hausner L, Jekel K, Richter M, Froelich L, Almkvist O, Boada M, Bullock R, De Deyn PP, Frisoni GB, Hampel H, Jones RW, Kehoe P, Lenoir H, Minthon L, Olde Rikkert MGM, Rodriguez G, Scheltens P, Soininen H, Spiru L, Touchon J, Tsolaki M, Vellas B, Verhey FRJ, Winblad B, Wahlund LO, Wilcock G, Visser PJ.
A longitudinal follow-up of 550 Mild Cognitive Impairment patients: evidence for large conversión to dementia rates and detection of major risk factors involved
Espinosa A, Alegret M, Valero S, Vinyes-Junqué G, Hernández I, Mauleón A, Rosende-Roca M, Ruiz A, López O, Tárraga L, Boada M.
Several Direct and Calculated Biomarkers from the Amyloid-β Pool in Blood are Associated with an Increased Likelihood of Suffering from Mild Cognitive Impairment
Pérez-Grijalba V, Pesini P, Monleón I, Boada M, Tárraga L, Ruiz-Laza A, Martínez-Lage P, San-José I, Sarasa M.
Transdermal is better than oral: observational research of the satisfaction of caregivers of patients with Alzheimer’s disease treated with rivastigmine
Boada M, Arranz FJ.
Genetic Study of Neurexin and Neuroligin Genes in Alzheimer's Disease
J Alzheimers Dis. 2013; I.F. 4.18 doi:35(2):403-12
Martínez-Mir A, González-Pérez A, Gayan J, Antúnez C, Marin J, Boada M, López-Arrieta, JK, Fernández E, Ruiz A, Gómez Scholl F, Real LM.
Utilidad de la Lista de Palabras de la Wechsler Memory Scale-III para valorar la memoria episódica verbal en la evaluación forense
Alegret M, Espinosa A, Ibarria M, Cañabate P, Boada M.
Atenció a persones amb demència i la seva família
Revista de Treball Social. Col·legi Oficial de Treball Social de Catalunya, abril 2013,
nº 198, pàgines 92-97. ISSN 0212-7210.
Cañabate P; Moreno M; Cerdán M.
Total impact factor: 127,5
Treatment of Alzheimer disease using combination therapy with plasma exchange and haemapheresis with albumin and intravenous immunoglobulin: Rationale and treatment approach of the AMBAR (Alzheimer Management By Albumin Replacement) study
Boada M, Ramos-Fernández E, Guivernau B, Muñoz FJ, Costa M, Ortiz AM, Jorquera JI, Núñez L, Torres M, Páez A.
Convergent genetic and expression data implicate immunity in Alzheimer's disease
Alzheimers Dement. 2015 Jun; I.F. 17.47 doi:11(6):658-71.
International Genomics of Alzheimer's Disease Consortium IGAP.
Association of TMEM106B rs1990622 Marker and Frontotemporal Dementia: Evidence for a Recessive Effect and Meta-Analysis
J Alzheimers Dis. 2015; I.F. 4.51 doi:43(1):325-34.
Hernández I, Rosende-Roca M, Alegret M, Mauleón A, Espinosa A, Vargas L, Sotolongo-Grau O, Tárraga L, Boada M, Ruiz A.
A Phase II Trial of Tideglusib in Alzheimer's Disease
Lovestone S, Boada M, Dubois B, Hüll M, Rinne JO, Huppertz HJ, Calero M, Andrés MV, Gómez-Carrillo B, León T, Del Ser T.
Aβ1-17 is a Major Amyloid-β Fragment Isoform in Cerebrospinal Fluid and Blood with Possible Diagnostic Value in Alzheimer's Disease
Pérez-Grijalba V, Pesini P, Allué JA, Sarasa L, Montañés M, Lacosta AM, Casabona D, San-José I, Boada M, Tárraga L, Ruiz A, Sarasa M.
A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis
Morón FJ, Velasco J, Marginet-Flinch R, Musulén E, Carrasco JM, Moreno-Rey C, Vázquez E, Chaves-Conde M, Moreno-Nogueira JA, Hidalgo-Pascual M, Ferrero-Herrero E, Castellví-Bel S, Castells A, Fernandez-Rozadilla C, Ruiz-Ponte C, Carracedo A, González B, Alonso S, Perucho M.
Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes
Neurobiol Aging. 2014 Nov; I.F. 4,85 doi:35(11):2657.e13-9.
Thelen M, Razquin C, Hernández I, Gorostidi A, Sánchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Martínez M, Rene R, Kornhuber J, Peters O, Luckhaus C, Jahn H, Hüll M, Rüther E, Wiltfang J, Lorenzo E, Gascon J, Lleó A, Lladó A, Campdelacreu J, Moreno F, Ahmadzadehfar H; Dementia Genetics Spanish Consortium (DEGESCO), Fortea J, Indakoetxea B, Heneka MT, Wetter A, Pastor MA, Riverol M, Becker T, Frölich L, Tárraga L, Boada M, Wagner M, Jessen F, Maier W, Clarimón J, López de Munain A, Ruiz A, Pastor P, Ramirez A.
Multiple organ involvement by alpha-synuclein pathology in Lewy body disorders
Mov Disord. 2014 Jul;29(8):1010-8. I.F. 5,63 doi: 10.1002/mds.25776. Epub 2014 Jan 2.
Gelpi E, Navarro-Otano J, Tolosa E, Gaig C, Compta Y, Rey MJ, Martí MJ, Hernández I, Valldeoriola F, Reñé R, Ribalta T.
Cognitive, genetic, and brain perfusion factors associated with four year incidence of Alzheimer's disease from mild cognitive impairment
Alegret M, Cuberas-Borrós G, Espinosa A, Valero S, Hernández I, Ruíz A, Becker JT, Rosende-Roca M, Mauleón A, Sotolongo O, Castell-Conesa J, Roca I, Tárraga L, Boada M
Effects of Gingko biloba supplementation in Alzheimer's disease patients receiving cholinesterase inhibitors: data from the ICTUS study
Canevelli M, Adali N, Kelaiditi E, Cantet C, Ousset PJ, Cesari M; ICTUS/DSA Group.
A 2-year prospective cohort study of antidementia drug non-persistency in mild-to-moderate Alzheimer's disease in Europe : predictors of discontinuation and switch in the ICTUS study
Gardette V, Lapeyre-Mestre M, Piau A, Gallini A, Cantet C, Montastruc JL, Vellas B, Andrieu S;
A phase 2 trial of the GSK-3 inhibitor tideglusib in progressive supranuclear palsy
Mov Disord. 2014 Apr;29(4):470-8. I.F. 5,63 doi: 10.1002/mds.25824
Tolosa E, Litvan I, Höglinger GU, Burn D, Lees A, Andrés MV, Gómez-Carrillo B, León T, Del Ser T; TAUROS Investigators.
Frontotemporal dementia and its subtypes: a genome-wide association study
Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, Hernández I, Ruiz A, Boada M, Borroni B, Padovani A, Cruchaga C, Cairns NJ, Benussi L, Binetti G, Ghidoni R, Forloni G, Galimberti D, Fenoglio C, Serpente M, Scarpini E, Clarimón J, Lleó A, Blesa R, Waldö ML, Nilsson K, Nilsson C, Mackenzie IR, Hsiung GY, Mann DM, Grafman J, Morris CM, Attems J, Griffiths TD, McKeith IG, Thomas AJ, Pietrini P, Huey ED, Wassermann EM, Baborie A, Jaros E, Tierney MC, Pastor P, Razquin C, Ortega-Cubero S, Alonso E, Perneczky R, Diehl-Schmid J, Alexopoulos P, Kurz A, Rainero I, Rubino E, Pinessi L, Rogaeva E, St George-Hyslop P, Rossi G, Tagliavini F, Giaccone G, Rowe JB, Schlachetzki JC, Uphill J, Collinge J, Mead S, Danek A, Van Deerlin VM, Grossman M, Trojanowski JQ, van der Zee J, Deschamps W, Van Langenhove T, Cruts M, Van Broeckhoven C, Cappa SF, Le Ber I, Hannequin D, Golfier V, Vercelletto M, Brice A, Nacmias B, Sorbi S, Bagnoli S, Piaceri I, Nielsen JE, Hjermind LE, Riemenschneider M, Mayhaus M, Ibach B, Gasparoni G, Pichler S, Gu W, Rossor MN, Fox NC, Warren JD, Spillantini MG, Morris HR, Rizzu P, Heutink P, Snowden JS, Rollinson S, Richardson A, Gerhard A, Bruni AC, Maletta R, Frangipane F, Cupidi C, Bernardi L, Anfossi M, Gallo M, Conidi ME, Smirne N, Rademakers R, Baker M, Dickson DW, Graff-Radford NR, Petersen RC, Knopman D, Josephs KA, Boeve BF, Parisi JE, Seeley WW, Miller BL, Karydas AM, Rosen H, van Swieten JC, Dopper EG, Seelaar H, Pijnenburg YA, Scheltens P, Logroscino G, Capozzo R, Novelli V, Puca AA, Franceschi M, Postiglione A, Milan G, Sorrentino P, Kristiansen M, Chiang HH, Graff C, Pasquier F, Rollin A, Deramecourt V, Lebert F, Kapogiannis D, Ferrucci L, Pickering-Brown S, Singleton AB, Hardy J, Momeni P
Gene-wide analysis detects two new susceptibility genes for Alzheimer’s disease
PLoS One. 2014 Jun I.F. 3,73 doi:12;9(6):e94661.
Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G1, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M; United Kingdom Brain Expression Consortium, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernández I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-García A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J.
Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial
Mov Disord. 2014 Apr; I.F. 5,63 doi:29(4):479-87. Boada M, Lafuente A cited as collaborators
Höglinger GU1, Huppertz HJ, Wagenpfeil S, Andrés MV, Belloch V, León T, Del Ser T; TAUROS MRI Investigators.
Methylglyoxal Produced by Amyloid-β Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer's Disease
Tajes M, Eraso-Pichot A, Rubio-Moscardó F, Guivernau B, Ramos-Fernández E, Bosch-Morató M, Guix FX, Clarimón J, Miscione GP, Boada M, Gil-Gómez G, Suzuki T, Molina H, Villà-Freixa J, Vicente R, Muñoz FJ.
Approaching allelic probabilities and Genome-Wide Association Studies from beta distributions
arXiv:1402.6151 [q-bio.GN] 25 feb 2014
J. Santiago García-Cremades, Ángel del Río, José A. García, Javier Gayán, Antonio González-Pérez, Agustín Ruiz, Oscar Sotolongo-Grau, Manuel Ruiz-Marín.
Posttranslational Nitro-Glycative Modifications of Albumin in Alzheimer's Disease: Implications in Cytotoxicity and Amyloid-β Peptide Aggregation
Ramos-Fernández E, Tajes M, Palomer E, Ill-Raga G, Bosch-Morató M, Guivernau B, Román-Dégano I, Eraso-Pichot A, Alcolea D, Fortea J, Nuñez L, Paez A, Alameda F, Fernández-Busquets X, Lleó A, Elosúa R, Boada M, Valverde MA, Muñoz FJ.
Association between cell-bound blood amyloid-β(1–40) levels and hippocampus volume
Sotolongo-Grau O, Pesini P, Valero S, Lafuente A, Buendia M, Pérez-Grijalba V, José IS, Ibarria M, Tejero MA, Giménez J, Hernández I, Tárraga L, Ruiz A, Boada M, Sarasa M.
Prevention of Alzheimer’s Disease: A Global Challenge for Next Generation Neuroscientists
Rodríguez-Gómez O, Palacio-Lacambra ME, Palasí A, Ruiz-Laza A, Boada-Rovira M.
Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration
Van der Zee J, Van Langenhove T, Kovacs GG, Dillen L, Deschamps W, Engelborghs S, Matěj R, Vandenbulcke M, Sieben A, Dermaut B, Smets K, Van Damme P, Merlin C, Laureys A, Van Den Broeck M, Mattheijssens M, Peeters K, Benussi L, Binetti G, Ghidoni R, Borroni B, Padovani A, Archetti S, Pastor P, Razquin C, Ortega-Cubero S, Hernández I, Boada M, Ruiz A, de Mendonça A, Miltenberger-Miltényi G, do Couto FS, Sorbi S, Nacmias B, Bagnoli S, Graff C, Chiang HH, Thonberg H, Perneczky R, Diehl-Schmid J, Alexopoulos P, Frisoni GB, Bonvicini C, Synofzik M, Maetzler W, Vom Hagen JM, Schöls L, Haack TB, Strom TM, Prokisch H, Dols-Icardo O, Clarimón J, Lleó A, Santana I, Almeida MR, Santiago B, Heneka MT, Jessen F, Ramirez A, Sanchez-Valle R, Llado A, Gelpi E, Sarafov S, Tournev I, Jordanova A, Parobkova E, Fabrizi GM, Testi S, Salmon E, Ströbel T, Santens P, Robberecht W, De Jonghe P, Martin JJ, Cras P, Vandenberghe R, De Deyn PP, Cruts M, Sleegers K, Van Broeckhoven C.
Utilidad del subtest Semejanzas de la Escala de Inteligencia de Wechsler para Adultos-III y su relación con la conciencia de déficit en la evaluación forense del deterioro cognitivo
Espinosa A, Alegret A, Ibarria M, Ortega G, Cañabate P, Boada M.
Follow up of loci from the International Genomics of Alzheimer’s Disease Project identifies TRIP4 as a novel susceptibility gene
Ruiz A, Heilmann S, Becker T, Hernández I, Wagner H, Thelen M, Mauleón A, Rosende-Roca M, Bellenguez C, Bis JC, Harold D, Gerrish A, Sims R, Sotolongo-Grau O, Espinosa A, Alegret M, Arrieta JL, Lacour A, Leber M, Becker J, Lafuente A, Ruiz S, Vargas L, Rodríguez O, Ortega G, Dominguez MA; IGAP, Mayeux R, Haines JL, Pericak-Vance MA, Farrer LA, Schellenberg GD, Chouraki V, Launer LJ, van Duijn C, Seshadri S, Antúnez C, Breteler MM, Serrano-Ríos M, Jessen F, Tárraga L, Nöthen MM, Maier W, Boada M, Ramírez A.
Valoración de las funciones visuoperceptivas y visuoespaciales en la práctica forense
Rev Esp Med Legal. 2014;40:83-5. I.F. 0,22
Ortega G, Alegret M, Espinosa A, Ibarria M, Cañabate P, Boada M.
Total impact factor: 135.03
MAPT H1 Haplotype is Associated with Late-Onset Alzheimer's Disease Risk in APOEɛ4 Noncarriers: Results from the Dementia Genetics Spanish Consortium
Pastor P, Moreno F, Clarimón J, Ruiz A, Combarros O, Calero M, López de Munain A, Bullido MJ, de Pancorbo MM, Carro E, Antonell A, Coto E, Ortega-Cubero S, Hernandez I, Tárraga L, Boada M, Lleó A, Dols-Icardo O, Kulisevsky J, Vázquez-Higuera JL, Infante J, Rábano A, Fernández-Blázquez MÁ, Valentí M, Indakoetxea B, Barandiarán M, Gorostidi A, Frank-García A, Sastre I, Lorenzo E, Pastor MA, Elcoroaristizabal X, Lennarz M, Maier W, Rámirez A, Serrano-Ríos M, Lee SE, Sánchez-Juan P
Diagostic accuracy of FTD behavioural frontotemporal dementia criteria in a clinicopathological cohort
Neuropathol Appl Neurobiol. 2015 Dec; I.F. 3.93 doi:41(7):882-92.
Balasa M, Gelpi E, Martín I, Antonell A, Rey M, Grau-Rivera O, Molinuevo J, Sánchez-Valle R, Lladó A; Catalan collaborative Study Group for FTLD.
Analysis of the CHCHD10 gene in patients with frontotemporal dementia and amyotrophic lateral sclerosis from Spain
J. Brain. 2015 Dec; I.F. 9.19 doi:138(Pt 12):e400.
Dols-Icardo, O , Nebot I , Gorostidi A, Ortega-Cubero S, Hernández I, Rojas-García R, García-Redondo A, Povedano M, Lladó A, Álvarez V, Sánchez-Juan P, Pardo J , Jericó I, Vázquez-Costa J, Sevilla T, Cardona F, Indakoechea B, Moreno F, Fernández-Torrón R, Muñoz-Llahuna L, Moreno-Grau S, Rosende-Roca M, Vela A, Muñoz-Blanco JL, Combarros O, Coto E, Alcolea D, Fortea J, Lleó A, Sánchez-Valle R, Esteban-Pérez J, Ruiz A, Pastor P, López De Munain A, Pérez-Tur J, Clarimón J
Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies
Rabin LA, Smart CM, Crane PK, Amariglio RE, Berman LM, Boada M, Buckley RF, Chételat G, Dubois B, Ellis KA, Gifford KA, Jefferson AL, Jessen F, Katz MJ, Lipton RB, Luck T, Maruff P, Mielke MM, Molinuevo JL, Naeem F, Perrotin A, Petersen RC, Rami L, Reisberg B, Rentz D, Riedel-Heller SG, Risacher SL, Rodriguez O, Sachdev PS, Saykin AJ, Slavin MJ, Snitz BE, Sperling RA, Tandetnik C, van der Flier WM, Wagner M, Wolfsgruber S, Sikkes SA.
Validation of the Spanish Version of the Face Name Associative Memory Exam (S-FNAME) in Cognitively Normal Older Individuals
Arch Clin Neuropsychol. 2015 Nov; I.F. 1.99 doi:30(7):712-20.
Alegret M, Valero S, Ortega G, Espinosa A, Sanabria A, Hernández I, Rodríguez O, Rosende-Roca M, Mauleón A, Vargas L, Martín E, Ruíz A, Tárraga L, Amariglio RE, Rentz DM, Boada M.
Influence of Sampling and Recruitment Methods in Studies of Subjective Cognitive Decline
J Alzheimers Dis. 2015 Sep I.F. 4.15 doi:24;48 Suppl 1:S99-S107.
Rodríguez-Gómez O, Abdelnour C, Jessen F, Valero 3, Boada M.
Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study
Neurobiol Aging. 2015 May; I.F. 5.01 doi:36(5):2005.e15-22.
Cuyvers E, van der Zee J, Bettens K, Engelborghs S, Vandenbulcke M, Robberecht C, Dillen L, Merlin C, Geerts N, Graff C, Thonberg H, Chiang HH, Pastor P, Ortega-Cubero S, Pastor MA, Diehl-Schmid J, Alexopoulos P, Benussi L, Ghidoni R, Binetti G, Nacmias B, Sorbi S, Sanchez-Valle R, Lladó A, Gelpi E, Almeida MR, Santana I, Clarimon J, Lleó A, Fortea J, de Mendonça A, Martins M, Borroni B, Padovani A, Matěj R, Rohan Z, Ruiz A, Frisoni GB, Fabrizi GM, Vandenberghe R, De Deyn PP, Van Broeckhoven C, Sleegers K; BELNEU Consortium and of the EU EOD Consortium.
Differentiated clinical presentation of early and late-onset Alzheimer's disease: is 65 years of age providing a reliable threshold?
Palasí A, Gutiérrez-Iglesias B, Alegret M, Pujadas F, Olabarrieta M, Liébana D, Quintana M, Álvarez-Sabín J, Boada M.
PLD3 in non-familial Alzheimer's disease
Nature. 2015 Apr F.I. 41.45 doi:2;520(7545):E3-5.
Heilmann S, Drichel D, Clarimon J, Fernández V, Lacour A, Wagner H, Thelen M, Hernández I, Fortea J, Alegret M, Blesa R, Mauleón A, Roca MR, Kornhuber J, Peters O, Heun R, Frölich L, Hüll M, Heneka MT, Rüther E, Riedel-Heller S, Scherer M, Wiltfang J, Jessen F, Becker T, Tárraga L, Boada M, Maier W, Lleó A, Ruiz A, Nöthen MM, Ramirez A.
Assessing the Role of TUBA4A Gene in Frontotemporal Degeneration
Dols-Icardo O, Iborra O, Valdivia J, Pastor P, Ruiz A, López de Munain A, Sánchez-Valle R, Álvarez V, Sánchez-Juan P, Lleó A, Fortea J, Blesa R, Cardona F, Baquero M, Alonso MD, Ortega-Cubero S, Pastor MA, Razquin C, Boada M, Hernández I, Gorostidi A, Moreno F, Zulaica M, Lladó A, Coto E, Combarros O, Pérez-Tur J, Clarimón J on behalf of The Dementia Genetics Spanish Consortium (DEGESCO).
A Truncating Mutation in Alzheimer’s Disease Inactivates Neuroligin-1 Synaptic Function
Tristán-Clavijo, E, Camacho-Garcia, R J, Robles-Lanuza, E, Ruiz, A, van der Zee, J, Van Broeckhoven, C, Hernández I, Martínez-Mir A, Scholl, F G (2015)
A novel Alzheimer disease locus located near the gene encoding tau protein
Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellengez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL7, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH Jr, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L; IGAP Consortium, Haines JL, Psaty BM, Van Broeckhoven C, Holmans P, Launer LJ, Mayeux R, Lathrop M, Goate AM, Escott-Price V, Seshadri S, Pericak-Vance MA, Amouyel P, Williams J, van Duijn CM, Schellenberg GD, Farrer LA.
Concordance between Subjective and Objective Memory Impairment in Volunteer Subjects
Alegret M, Rodríguez O, Espinosa A, Ortega G, Sanabria A, Valero S, Hernández I, Rosende-Roca M, Vargas L, Abdelnour C, Mauleón A, Gailhajanet A, Martín E, Tárraga L, Rentz DM, Amariglio RE, Ruíz A, Boada M.
Evaluation of Candidate Genes Related to Neuronal Apoptosis in Late-Onset Alzheimer's Disease
Moreno-Grau S, Barneda B, Carriba P, Marín J, Sotolongo-Grau O, Hernández I, Rosende-Roca M, Mauleón A, Vargas L, Espinosa A, Alegret M, Rodriguez O, Ortega G, Fernández MV, López-Arrieta J, Tárraga L, Boada M, Antúnez C, López J, Ruiz A, Comella JX J
Retirement age and the age of onset of Alzheimer's disease: results from the ICTUS study
Grotz C, Letenneur L, Bonsang E, Amieva H, Meillon C, Quertemont E, Salmon E, Adam S; ICTUS/DSA group.
Total impact factor: 79.26
Shared genetic contribution to ischemic stroke and Alzheimer's disease
Ann Neurol. 2016 May; I.F. 9.98 doi: 79(5): 739–747.
Matthew Traylor, Poneh Adib‐Samii, Denise Harold, the Alzheimer's Disease Neuroimaging Initiative, The International Stroke Genetics Consortium (ISGC), UK Young Lacunar Stroke DNA resource, Martin Dichgans, Julie Williams, Cathryn M. Lewis, Hugh S. Markus, and and the METASTROKE and International Genomics of Alzheimer's Project (IGAP) investigators.
TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
van der Zee J, Gijselinck I, Van Mossevelde S, Perrone F, Dillen L, Heeman B, Bäumer V, Engelborghs S, De Bleecker J, Baets J, Gelpi E, Rojas-García R, Clarimón J, Lleó A, Diehl-Schmid J, Alexopoulos P, Perneczky R, Synofzik M, Just J, Schöls L, Graff C, Thonberg H, Borroni B, Padovani A, Jordanova A, Sarafov S, Tournev I, de Mendonça A, Miltenberger-Miltényi G, Simões do Couto F, Ramirez A, Jessen F, Heneka MT, Gómez-Tortosa E, Danek A, Cras P, Vandenberghe R, De Jonghe P, De Deyn PP, Sleegers K, Cruts M, Van Broeckhoven C, Goeman J, Nuytten D, Smets K, Robberecht W, Damme PV, Bleecker J, Santens P, Dermaut B, Versijpt J, Michotte A, Ivanoiu A, Deryck O, Bergmans B, Delbeck J, Bruyland M, Willems C, Salmon E, Pastor P, Ortega-Cubero S, Benussi L, Ghidoni R, Binetti G, Hernández I, Boada M, Ruiz A, Sorbi S, Nacmias B, Bagnoli S, Sorbi S, Sanchez-Valle R, Llado A, Santana I, Rosário Almeida M, Frisoni GB, Maetzler W, Matej R, Fraidakis MJ, Kovacs GG, Fabrizi GM, Testi S.
Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial
Boada M, Anaya F, Ortiz P, Olazarán J, Shua-Haim JR, Obisesan TO, Hernández I, Muñoz J, Buendia M, Alegret M, Lafuente A, Tárraga L, Núñez L, Torres M, Grifols JR, Ferrer I, Lopez OL, Páez A.
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
J Neurol Neurosurg Psychiatry. 2017 Feb; F.I. 6.81 doi:88(2):152-164.
Ferrari R, Wang Y, Vandrovcova J, Guelfi S, Witeolar A, Karch CM, Schork AJ, Fan CC, Brewer JB; International FTD-Genomics Consortium (IFGC), International Parkinson's Disease Genomics Consortium (IPDGC), International Genomics of Alzheimer's Project (IGAP), Momeni P, Schellenberg GD, Dillon WP, Sugrue LP, Hess CP, Yokoyama JS, Bonham LW, Rabinovici GD, Miller BL, Andreassen OA, Dale AM, Hardy J, Desikan RS.
Genome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment
Lacour A, Espinosa A, Louwersheimer E, Heilmann S, Hernández I, Wolfsgruber S, Fernández V, Wagner H, Rosende-Roca M, Mauleón A, Moreno-Grau S, Vargas L, Pijnenburg YA, Koene T, Rodríguez-Gómez O, Ortega G, Ruiz S, Holstege H, Sotolongo-Grau O, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E, Wiltfang J, Scherer M, Riedel-Heller S, Alegret M, Nöthen MM, Scheltens P, Wagner M, Tárraga L, Jessen F, Boada M, Maier W, van der Flier WM, Becker T, Ramirez A, Ruiz A
Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment
Louwersheimer E, Wolfsgruber S, Espinosa A, Lacour A, Heilmann-Heimbach S, Alegret M, Hernández I, Rosende-Roca M, Tárraga L, Boada M, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E1, Wiltfang J, Scherer M, Riedel-Heller S, Jessen F, Nöthen MM, Maier W, Koene T, Scheltens P, Holstege H, Wagner M, Ruiz A, van der Flier WM, Becker T, Ramirez A.
Beneficial Effects of an Integrated Psychostimulation Program in Patients with Alzheimer's Disease
J Alzheimers Dis. 2015; I.F. 4.15 doi:50(2):559-66.
Ibarria M, Alegret M, Valero S, Morera A, Guitart M, Cañabate P, Moreno M, Lara S, Diego S, Hernández J, Tantinyá N, Vera M, Hernández I, Becker JT, Ruíz A, Boada M, Tárraga L.
Registries and Cohorts to Accelerate Early Phase Alzheimer's Trials. A Report from the E.U./U.S. Clinical Trials in Alzheimer's Disease Task Force
Aise P, Touchon J, Andrieu S, Boada M, Doody R, Nosheny RL, Langbaum JB, Schneider L, Hendrix S, Wilcock G, Molinuevo JL, Ritchie C, Ousset P-J, Cummings J, Sperling R, DeKsky ST, Lovestone S, Hampel H, Petersen R, Legrand V, Egan M, Randolph C, Salloway S, Weiner M, Vellas B and Task Force members.
FACEHBI: A Prospective Study Of Risk Factors, Biomarkers and Cognition in a Cohort of Individuals with Subjective Cognitive Decline. Study Rationale and Research Protocols
O. Rodriguez-Gomez, A. Sanabria, A. Perez-Cordon, D. Sanchez-Ruiz, C. Abdelnour, S. Valero, I. Hernandez, M. Rosende-Roca, A. Mauleon, L. Vargas, M. Alegret, A. Espinosa, G. Ortega, M. Guitart, A. Gailhajanet, O. Sotolongo-Grau, S. Moreno-Grau, S. Ruiz, M. Tarragona, J. Serra, E. Martin, E. Peleja, F. Lomeña, F. Campos, A. Vivas, M.Gomez-Chiari, M.A. Tejero, J. Giménez, P. Pesini, M. Sarasa, G.Martinez, A. Ruiz, L. Tarraga, M.Boada.
Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke
Thromb Haemost. 2016 Nov doi:30;116(6):1165-1171. Epub 2016 Sep 8.
Carrera C, Jiménez-Conde J, Derdak S, Rabionet K, Vives-Bauzá C, Soriano-Tárrega C, Giralt-Steinhauer E, Mola M, Diaz-Navarro RM, Tur S, Muiño E, Gallego-Fabrega C, Beltran S, Roquer J, Ruiz A, Sotolongo-Grau O, Krupinski J, Lee JM, Cruchaga C, Delgado P, Malik R, Worrall BB, Seshadri S, Montaner J, Fernández-Cadenas I1; Metastroke Consortium, ISGC Consortium and Genestroke Consortium.
Alzheimer's disease cerebrospinal fluid biomarkers predict cognitive decline in lewy body dementia
Abdelnour C, van Steenoven I, Londos E, Blanc F, Auestad B, Kramberger MG, Zetterberg H, Mollenhauer B, Boada M, Aarsland D; European DLB Consortium
Bapineuzumab for mild to moderate Alzheimer's disease in two global, randomized, phase 3 trials
Alzheimers Res Ther. 2016 May 12;8(1):18. doi: 10.1186/s13195-016-0189-7
Vandenberghe R, Rinne JO, Boada M, Katayama S, Scheltens P, Vellas B, Tuchman M, Gass A, Fiebach JB, Hill D, Lobello K, Li D, McRae T, Lucas P, Evans I, Booth K, Luscan G, Wyman BT, Hua L, Yang L, Brashear HR, Black RS; Bapineuzumab 3000 and 3001 Clinical Study Investigators.
Genome research in pre-dementia stages of Alzheimer's disease
Expert Rev Mol Med. 2016 May 30;18:e11. doi: 10.1017/erm.2016.12.
Moreno-Grau S, Ruiz A. Expert Rev
Total impact factor: 133.82
Exploring APOE genotype effects on AD risk and beta-amyloid burden in individuals with subjective cognitive decline: the FACEHBI study baseline results
Alzheimers Dement. 2018 May;14(5):634-643. F. I. 9.478. doi: 10.1016/j.jalz.2017.10.005. Epub 2017 Nov 20.
Sonia Moreno –Grau, O. Rodríguez-Gomez, A. Sanabria, A. Perez-Cordon, D. Sánchez-Ruiz, C. Abdelnour, S. Valero, I. Hernández, M. Rosende-Roca, A. Mauleón, L. Vargas, A. Lafuente, S. Gil, M. A. Santos-Santos, M. Alegret, A. Espinosa, G. Ortega, M. Guitart, A. Gailhajanet, I. de Rojas, O. Sotolongo-Grau, S. Ruiz, N. Aguilera, J. Papasey, E. Martín, E. Peleja, Alzheimer’s Disease Neuroimaging Initiative*, F. Lomeña, F. Campos, A. Vivas, M.Gomez-Chiari, M.A. Tejero, J. Giménez, M. Serrano-Ríos, A. Orellana, L. Tárraga, A. Ruiz, M.Boada, on behalf of the FACEHBI study group.
Frontotemporal Lobar Degeneration. Review and update for clinical neurologists
Curr Alzheimer Res. 2018;15(6):511-530. F. I. 2.952. doi: 10.2174/1567205014666170725130819. Epub 2017 Jul 25.
Hernández I, Fernández MV, Tàrraga L, Boada M, Ruiz A.
Genetic risk for schizophrenia and psychosis in Alzheimer disease
Mol Psychiatry. 2018 Apr;23(4):963-972. F.I. 13.204. doi: 10.1038/mp.2017.81. Epub 2017 May 2.
DeMichele-Sweet MAA, Weamer EA, Klei L, Vrana DT, Hollingshead DJ, Seltman HJ, Sims R, Foroud T, Hernandez I, Moreno-Grau S, Tárraga L, Boada M, Ruiz A, Williams J, Mayeux R, Lopez OL, Sibille EL, Kamboh MI, Devlin B, Sweet RA.
A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease
Alzheimers Res Ther. 2017 Dec 8;9(1):95. F.I. 6.154. doi: 10.1186/s13195-017-0318-y.
Ostrowitzki S, Lasser RA, Dorflinger E, Scheltens P, Barkhof F, Nikolcheva T, Ashford E, Retout S, Hofmann C, Delmar P, Klein G, Andjelkovic M, Dubois B, Boada M, Blennow K, Santarelli L, Fontoura P; SCarlet RoAD Investigators.
Retinal Microperimetry: A New Tool for Identifying Type 2 Diabetic Patients at Risk of DevelopingAlzheimer´s Disease
Diabetes. 2017 Dec;66(12):3098-3104. F. I. 8.684. doi: 10.2337/db17-0382. Epub 2017 Sep 26.
Ciudin A, Simó-Servat O, Hernández C, Arcos G, Diego S, Sanabria Á, Sotolongo Ó, Hernández I, Boada M, Simó R.
18F PET with florbetaben for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
Cochrane Database Syst Rev. 2017 Nov 22;11:CD012883. F.I. 6.12. doi: 10.1002/14651858.CD012883.
Martínez G, Vernooij RW, Fuentes Padilla P, Zamora J, Flicker L, Bonfill Cosp X.
18F PET with flutemetamol for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
Cochrane Database Syst Rev. 2017 Nov 22;11:CD012884. F.I. 6.12. doi: 10.1002/14651858.CD012884.
Martínez G, Vernooij RW, Fuentes Padilla P, Zamora J, Flicker L, Bonfill Cosp X.
18F PET with florbetapir for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
Cochrane Database Syst Rev. 2017 Nov 22;11:CD012216. F.I. 6.12. doi: 10.1002/14651858.CD012216.pub2.
Martínez G, Vernooij RW, Fuentes Padilla P, Zamora J, Bonfill Cosp X, Flicker L.
Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis
JAMA Neurol. 2017 Oct 1;74(10):1178-1189. F. I. 10.03. doi: 10.1001/jamaneurol.2017.2188.
Neu SC, Pa J, Kukull W, Beekly D, Kuzma A, Gangadharan P, Wang LS, Romero K, Arneric SP, Redolfi A, Orlandi D, Frisoni GB, Au R, Devine S, Auerbach S, Espinosa A, Boada M, Ruiz A, Johnson SC, Koscik R, Wang JJ, Hsu WC, Chen Y, Toga AW.
Registries and Cohorts to Accelerate Early Phase Alzheimer’s Trials. A Report from the E.U./U.S. Clinical Trials in Alzheimer’s Disease Task Force
J Prev Alz Dis 2016;3(2):68-74. doi: 10.14283/jpad.2016.97
P. Aisen, J. Touchon, S. Andrieu, M. Boada, R. Doody, R.L. Nosheny, J.B. Langbaum, L. Schneider, S. Hendrix, G. Wilcock, J.L. Molinuevo, C. Ritchie, P.-J. Ousset, J. Cummings, R. Sperling, S.T. DeKosky, S. Lovestone, H. Hampel, R. Petersen, V. Legrand, M. Egan, C. Randolph, S. Salloway, M. Weiner, B. Vellas, and Task Force Members.
A physical model for dementia
Physica A. 2017 Apr 15;472:86-93. doi:10.1016/j.physa.2016.12.086. Epub 2017 Jan 4.
O. Sotolongo-Costa, L.M. Gaggero-Sager, J.T. Becker, F. Maestuf, O. Sotolongo-Grau, for the Alzheimer’s Disease Neuroimaging Initiative.
The impact of automated hippocampal volumetry on diagnostic confidence in patients with suspected Alzheimer's disease: An EADC study
Alzheimers Dement. 2017 Sep;13(9):1013-1023. I.F. 11,619. doi: 10.1016/j.jalz.2017.01.019. Epub 2017
Mar 3
Bosco P, Redolfi A, Bocchetta M, Ferrari C, Mega A, Galluzzi S, Austin M, Chincarini A, Collins DL, Duchesne S, Maréchal B, Roche A, Sensi F, Wolz R, Alegret M, Assal F, Balasa M, Bastin C, Bougea A, Emek-Savaş DD, Engelborghs S, Grimmer T, Grosu G, Kramberger MG, Lawlor B, Mandic Stojmenovic G, Marinescu M, Mecocci P, Molinuevo JL, Morais R, Niemantsverdriet E, Nobili F, Ntovas K, O'Dwyer S, Paraskevas GP, Pelini L, Picco A, Salmon E, Santana I, Sotolongo-Grau O, Spiru L, Stefanova E, Popovic KS, Tsolaki M, Yener GG, Zekry D, Frisoni GB.
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Nat Genet. 2017 Sep;49(9):1373-1384. F.I. 27.959 (2 years). doi: 10.1038/ng.3916. Epub 2017 Jul 17.
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Jr WTL, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J; ARUK Consortium, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM2, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, Lipton RB, Bullido M, Hofman A, Montine TJ, Coto E, Boerwinkle E, Petersen RC, Alvarez V, Rivadeneira F, Reiman EM, Gallo M, O'Donnell C, Reisch JS, Bruni AC, Royall DR, Dichgans M, Sano M, Galimberti D, St George-Hyslop P, Scarpini E, Tsuang DW, Mancuso M, Bonuccelli U, Winslow AR, Daniele A, Wu CK; GERAD/PERADES, CHARGE, ADGC, EADI, Peters O, Nacmias B, Riemenschneider M, Heun R, Brayne C, Rubinsztein DC, Bras J, Guerreiro R, Al-Chalabi A, Shaw CE, Collinge J, Mann D, Tsolaki M, Clarimón J, Sussams R, Lovestone S, O'Donovan MC, Owen MJ, Behrens TW, Mead S, Goate AM, Uitterlinden AG, Holmes C1, Cruchaga C, Ingelsson M, Bennett DA, Powell J, Golde TE, Graff C, De Jager PL, Morgan K, Ertekin-Taner N, Combarros O, Psaty BM, Passmore P, Younkin SG, Berr C, Gudnason V, Rujescu D, Dickson DW, Dartigues JF, DeStefano AL, Ortega-Cubero S, Hakonarson H, Campion D, Boada M, Kauwe JK, Farrer LA, Van Broeckhoven C, Ikram MA, Jones L, Haines JL, Tzourio C, Launer LJ, Escott-Price V, Mayeux R, Deleuze JF, Amin N, Holmans PA, Pericak-Vance MA, Amouyel P, van Duijn CM, Ramirez A, Wang LS, Lambert JC, Seshadri S, Williams J, Schellenberg GD.
Mapping the Health Information Landscape in a Rural, Culturally Diverse Region: Implications for Interventions to Reduce Information Inequality
J Prim Prev. 2017 Aug;38(4):345-362. I.F. 1,33. doi: 10.1007/s10935-017-0466-7.
Ramírez AS, Estrada E, Ruiz A.
Type 2 diabetes is an independent risk factor for dementia conversion in patients with mild cognitive impairment
J Diabetes Complications. 2017 Aug;31(8):1272-1274. F.I. 2.73. doi: 10.1016/j.jdiacomp.2017.04.018. Epub 2017 Apr 19.
Ciudin A, Espinosa A, Simó-Servat O, Ruiz A, Alegret M, Hernández C, Boada M, Simó R.
Sembragiline in Moderate Alzheimer's Disease: Results of a Randomized, Double-Blind, Placebo-Controlled Phase II Trial (MAyflOwer RoAD)
J Alzheimers Dis. 2017;58(4):1217-1228. F.I. 3.731. doi: 10.3233/JAD-161309.
Nave S, Doody RS, Boada M, Grimmer T, Savola JM, Delmar P, Pauly-Evers M, Nikolcheva T, Czech C, Borroni E, Ricci B, Dukart J, Mannino M, Carey T, Moran E, Gilaberte I, Muelhardt NM, Gerlach I, Santarelli L, Ostrowitzki S, Fontoura P.
Challenges for Service Robots-Requirements of Elderly Adults with Cognitive Impairments
Front Neurol. 2017 Jun 1;8:228. F.I. 6.4. doi: 10.3389/fneur.2017.00228. eCollection 2017.
Korchut A, Szklener S, Abdelnour C, Tantinya N, Hernández-Farigola J, Ribes JC, Skrobas U, Grabowska-Aleksandrowicz K, Szczęśniak-Stańczyk D, Rejdak K.
Social Representation of Dementia: An Analysis of 5,792 Consecutive Cases Evaluated in a Memory Clinic
J Alzheimers Dis. 2017;58(4):1099-1108. F.I. 3.731. doi: 10.3233/JAD-161119.
Cañabate P, Martínez G, Rosende-Roca M, Moreno M, Preckler S, Valero S, Sotolongo O, Hernández I, Alegret M, Ortega G, Espinosa A, Mauleón A, Vargas L, Rodríguez O, Abdelnour C, Sánchez D, Martín E, Ruiz A, Tárraga L, Boada M..
Cognitive Composites Domain Scores Related to Neuroimaging Biomarkers within Probable-Amnestic Mild Cognitive Impairment-Storage Subtype
J Alzheimers Dis. 2017;57(2):447-459. F.I. 3.731. doi: 10.3233/JAD-161223.
Espinosa A, Alegret M, Pesini P, Valero S, Lafuente A, Buendía M, San José I, Ibarria M, Tejero MA, Giménez J, Ruiz S, Hernández I, Pujadas F, Martínez-Lage P, Munuera J, Arbizu J, Tárraga L, Hendrix SB, Ruiz A, Becker JT, Landau SM, Sotolongo-Grau O, Sarasa M, Boada M.
Impact of Recruitment Methods in Subjective Cognitive Decline
J Alzheimers Dis. 2017;57(2):625-632. F.I. 3.731. doi: 10.3233/JAD-160915.
Abdelnour C, Rodríguez-Gómez O, Alegret M, Valero S, Moreno-Grau S, Sanabria Á, Hernández I, Rosende-Roca M, Vargas L, Mauleón A, Sánchez D, Espinosa A, Ortega G, Pérez-Cordón A, Diego S, Gailhajanet A, Guitart M, Sotolongo-Grau Ó, Ruiz A, Tárraga L, Boada M.
Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis
JAMA Neurol. 2017 Oct 1;74(10):1178-1189. F. I. 10.03 doi: 10.1001/jamaneurol.2017.2188.
J, Kukull W, Beekly D, Kuzma A, Gangadharan P, Wang LS, Romero K, Arneric SP, Redolfi A, Orlandi D, Frisoni GB, Au R, Devine S, Auerbach S, Espinosa A, Boada M, Ruiz A, Johnson SC, Koscik R, Wang JJ, Hsu WC, Chen Y, Toga AW.
Total impact factor: 211,45
Severity dependent distribution of impairments in PSP and CBS: Interactive visualizations
Parkinsonism and Related Disorders. 2018 Sep 4. pii: S1353-8020(18)30384-5. F.I. 4.721 doi: 10.1016/j.parkreldis.2018.08.025
Brittain C1, McCarthy A2, Irizarry MC3, McDermott D4, Biglan K3, Höglinger GU5, Lorenzl S6, Del Ser T7, Boxer AL4; AL-108-231 Study Group; PROPSPERA investigators; 4RNTI-1authors; Tau Restoration on PSP (TAUROS) Investigators.
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease
Peloso GM1, van der Lee SJ2; International Genomics of Alzheimer's Project (IGAP), Destefano AL1,3,4, Seshardi S3,4,5.
Anticancer Agents in Medicine Chemistry
Anticancer Agents Med Chem. 2018;18(4):591-596. doi: 10.2174/1871520618666180228123406.
Ruiz DS1, Luksch H2, Sifringer M3, Temme A4, Staufner C5, Rzeski W6,7, Marzahn J2, Grabarska A8, Ikonomidou C9, Stepulak A8.
AMPA Receptor Antagonist CFM-2 Decreases Survivin Expression in Cancer Cells
Anticancer Agents in Medicine Chemistry. 2018;18(4):591-596 F.I. 2.556 doi: 10.2174/1871520618666180228123406.
Ruiz DS, Luksch H, Sifringer M, Temme A, Staufner C, Rzeski W, Marzahn J, Grabarska A, Ikonomidou C, Stepulak A.
Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia
Alzheimers Dement. 2018 Dec 13. pii: S1552-5260(18)33563-5. F.I. 12,74 doi: 10.1016/j.jalz.2018.10.003
Slot RER1, Sikkes SAM2, Berkhof J3, Brodaty H4, Buckley R5, Cavedo E6, Dardiotis E7, Guillo-Benarous F8, Hampel H6, Kochan NA9, Lista S6, Luck T10, Maruff P11, Molinuevo JL12, Kornhuber J13, Reisberg B8, Riedel-Heller SG14, Risacher SL15, Roehr S16, Sachdev PS9, Scarmeas N17, Scheltens P1, Shulman MB8, Saykin AJ15, Verfaillie SCJ1, Visser PJ18, Vos SJB19, Wagner M20, Wolfsgruber S20, Jessen F21; Alzheimer's Disease Neuroimaging Initiative, the DESCRIPA working group, the INSIGHT-preAD study group, on behalf of the SCD-I working group, van der Flier WM22.
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
Nat Med. 2018 Dec 3. F.I. 32,62 doi: 10.1038/s41591-018-0223-3
Swarup V1, Hinz FI1, Rexach JE1, Noguchi KI2, Toyoshiba H2, Oda A2, Hirai K2, Sarkar A1, Seyfried NT3,4, Cheng C5, Haggarty SJ5; International Frontotemporal Dementia Genomics Consortium, Grossman M6, Van Deerlin VM7, Trojanowski JQ7, Lah JJ4, Levey AI4, Kondou S2, Geschwind DH8,9,10.
Correlations between plasma and PET beta-amyloid levels in individuals with subjective cognitive decline: the Fundació ACE Healthy Brain Initiative (FACEHBI)
Alzheimers Res Ther. 2018 Nov 29;10(1):119. F.I. 5.015 doi: 10.1186/s13195-018-0444-1
de Rojas I, Romero J, Rodríguez-Gomez O, Pesini P, Sanabria A, Pérez-Cordon A, Abdelnour C, Hernández I, Rosende-Roca M, Mauleón A, Vargas L, Alegret M, Espinosa A, Ortega G, Gil S, Guitart M, Gailhajanet A, Santos-Santos MA, Moreno-Grau S, Sotolongo-Grau O, Ruiz S, Montrreal L, Martín E, Pelejà E, Lomeña F, Campos F, Vivas A, Gómez-Chiari M, Tejero MA, Giménez J, Pérez-Grijalba V, Marquié GM, Monté-Rubio G, Valero S, Orellana A, Tárraga L, Sarasa M, Ruiz A*, Boada M; FACEHBI study.
Plasma Aβ42/40 Ratio Detects Early Stages of Alzheimer’s Disease and Correlates with CSF and Neuroimaging Biomarkers in the AB255 Study
J Prev Alzheimers Dis. 2019;6(1):34-41. doi: 10.14283/jpad.2018.41.
V. Pérez-Grijalba, J. Romero, P. Pesini, L. Sarasa, I. Monleón, I. San-José, J. Arbizu, P. Martínez-Lage, J. Munuera, A. Ruiz, L. Tárraga, M. Boada, M. Sarasa, on behalf of The AB255 Study Group.
Usefulness of peripapillary nerve fiber layer thickness assessed by optical coherence tomography as a biomarker for Alzheimer's disease
Nature Scientific Reports. 2018 Nov 5;8(1):16345 F.I. 4,122 doi: 10.1038/s41598-018-34577-3.
Sánchez D*, Castilla-Marti M, Rodríguez-Gómez O, Valero S, Piferrer A, Martínez G, Martínez J, Serra J, Moreno-Grau S, Hernández-Olasagarre B, De Rojas I, Hernández I, Abdelnour C, Rosende-Roca M, Vargas L, Mauleón A, Santos-Santos MA, Alegret M, Ortega G, Espinosa A, Pérez-Cordón A, Sanabria Á, Ciudin A, Simó R, Hernández C, Villaoslada P, Ruiz A, Tàrraga L, Boada M.
Exploring Genetic Associations of Alzheimer’s Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes
Frontiers in Aging Neuroscience, 2018 Oct 30;10:340. F.I. 3.582 doi:10.3389/fnagi.2018.00340.
Espinosa A, Hernández-Olasagarre B, Moreno-Grau S, Kleineidam L, Heilmann-Heimbach S, Hernández I, Wolfsgruber S, Wagner H, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Rodríguez-Gómez O, Abdelnour C, Gil S, Marquié M, Santos-Santos MA, Sanabria Á, Ortega G, Monté-Rubio G, Pérez A, Ibarria M, Ruiz S, Kornhuber J, Peters O, Frölich L, Hüll M, Wiltfang J, Luck T, Riedel-Heller S, Montrreal L, Cañabate P, Moreno M, Preckler S, Aguilera N, de Rojas I, Orellana A, Alegret M, Valero S, Nöthen MM, Wagner M, Jessen F, Tárraga L, Boada M, Ramírez A, Ruiz A*.
Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study
Alzheimers Res Ther. 2018 Aug 23;10(1):85. F.I. 5.015. doi: 10.1186/s13195-018-0415-6.
Timmers M1,2, Streffer JR3,4,5, Russu A3, Tominaga Y6, Shimizu H6, Shiraishi A6, Tatikola K7, Smekens P3, Börjesson-Hanson A8, Andreasen N9, Matias-Guiu J10, Baquero M11, Boada M12, Tesseur I3, Tritsmans L3, Van Nueten L3, Engelborghs S4,13.
Analysis of shared heritability in common disorders of the brain
Science. 2018 Jun 22;360(6395). pii: eaap8757 F.I. 41.058. doi: 10.1126/science.aap8757
Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono R, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CHD, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, De Rubeis S, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, Rogé B, Magalhaes T, Arking D, Schulze TG, Thompson RC, Strohmaier J, Matthews K, Melle I, Morris D, Blackwood D, McIntosh A, Bergen SE, Schalling M, Jamain S, Maaser A, Fischer SB, Reinbold CS, Fullerton JM, Guzman-Parra J, Mayoral F, Schofield PR, Cichon S, Mühleisen TW, Degenhardt F, Schumacher J, Bauer M, Mitchell PB, Gershon ES, Rice J, Potash JB, Zandi PP, Craddock N, Ferrier IN, Alda M, Rouleau GA, Turecki G, Ophoff R, Pato C, Anjorin A, Stahl E, Leber M, Czerski PM, Cruceanu C, Jones IR, Posthuma D, Andlauer TFM, Forstner AJ, Streit F, Baune BT, Air T, Sinnamon G, Wray NR, MacIntyre DJ, Porteous D, Homuth G, Rivera M, Grove J, Middeldorp CM, Hickie I, Pergadia M, Mehta D, Smit JH, Jansen R, de Geus E, Dunn E, Li QS, Nauck M, Schoevers RA, Beekman AT, Knowles JA, Viktorin A, Arnold P, Barr CL, Bedoya-Berrio G, Bienvenu OJ, Brentani H, Burton C, Camarena B, Cappi C, Cath D, Cavallini M, Cusi D, Darrow S, Denys D, Derks EM, Dietrich A, Fernandez T, Figee M, Freimer N, Gerber G, Grados M, Greenberg E, Hanna GL, Hartmann A, Hirschtritt ME, Hoekstra PJ, Huang A, Huyser C, Illmann C, Jenike M, Kuperman S, Leventhal B, Lochner C, Lyon GJ, Macciardi F, Madruga-Garrido M, Malaty IA, Maras A, McGrath L, Miguel EC, Mir P, Nestadt G, Nicolini H, Okun MS, Pakstis A, Paschou P, Piacentini J, Pittenger C, Plessen K, Ramensky V, Ramos EM, Reus V, Richter MA, Riddle MA, Robertson MM, Roessner V, Rosário M, Samuels JF, Sandor P, Stein DJ, Tsetsos F, Van Nieuwerburgh F, Weatherall S, Wendland JR, Wolanczyk T, Worbe Y, Zai G, Goes FS, McLaughlin N, Nestadt PS, Grabe HJ, Depienne C, Konkashbaev A, Lanzagorta N, Valencia-Duarte A, Bramon E, Buccola N, Cahn W, Cairns M, Chong SA, Cohen D, Crespo-Facorro B, Crowley J, Davidson M, DeLisi L, Dinan T, Donohoe G, Drapeau E, Duan J, Haan L, Hougaard D, Karachanak-Yankova S, Khrunin A, Klovins J, Kučinskas V, Lee Chee Keong J, Limborska S, Loughland C, Lönnqvist J, Maher B, Mattheisen M, McDonald C, Murphy KC, Nenadic I, van Os J, Pantelis C, Pato M, Petryshen T, Quested D, Roussos P, Sanders AR, Schall U, Schwab SG, Sim K, So HC, Stögmann E, Subramaniam M, Toncheva D, Waddington J, Walters J, Weiser M, Cheng W, Cloninger R, Curtis D, Gejman PV, Henskens F, Mattingsdal M, Oh SY, Scott R, Webb B, Breen G, Churchhouse C, Bulik CM, Daly M, Dichgans M, Faraone SV, Guerreiro R, Holmans P, Kendler KS, Koeleman B, Mathews CA, Price A, Scharf J, Sklar P, Williams J, Wood NW, Cotsapas C, Palotie A, Smoller JW, Sullivan P, Rosand J, Corvin A, Neale BM.
Systematic Screening of Ubiquitin/p62 Aggregates in Cerebellar Cortex Expands the Neuropathological Phenotype of the C9orf72 Expansion Mutation
J Neuropathol Exp Neurol. 2018 Jun 7 F.I. 3.490. doi: 10.1093/jnen/nly047
Ramos-Campoy O1,2, Ávila-Polo R1,3, Grau-Rivera O1,2, Antonell A2, Clarimón J4,5, Rojas-García R6, Charif S1, Santiago-Valera V1, Hernandez I7, Aguilar M8, Almenar C9, Lopez-Villegas D10, Bajo L11, Pastor P8, Van der Zee J12, Lladó A2, Sanchez-Valle R1,2, Gelpi E1,13.
A comparison of various MRI feature types for characterizing whole brain anatomical differences using linear pattern recognition methods
Neuroimage. 2018 Jun 2. pii: S1053-8119(18)30491-9 F.I. 5.426. doi: 10.1016/j.neuroimage.2018.05.065.
Monté-Rubio GC1, Falcón C2, Pomarol-Clotet E3, Ashburner J4.
Genome-wide significant risk factors on chromosome 19 and the APOE locus
Oncotarget. 2018 May 15;9(37):24590-24600. F.I. 5.426. doi: 10.18632/oncotarget.25083.
Moreno-Grau S1, Hernández I1, Heilmann-Heimbach S2,3, Ruiz S1, Rosende-Roca M1, Mauleón A1, Vargas L1, Rodríguez-Gómez O1, Alegret M1, Espinosa A1, Ortega G1, Aguilera N1, Abdelnour C1, Neuroimaging Initiative AD1,2,3,4,5,6,7,8,9, Gil S1, Maier W4,5, Sotolongo-Grau O1, Tárraga L1, Ramirez A2,4,6, López-Arrrieta J7, Antúnez C8, Serrano-Ríos M9, Boada M1, Ruiz A1.
Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing
BioRxiv. 10.1101/294629 doi:10.1101/294629
Brian W. Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C. Bis, Adam C. Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alex Amlie-Wolf, Celine Bellenguez, Aura Frizatti, Vincent Chouraki, Alzheimer's Disease Genetics Consortium (ADGC), European Alzheimer's Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in Alzheimer's Disease Consortium (GERAD/PERADES), Helena Schmidt, Hakon Hakonarson, Ron Munger, Reinhold Schmidt, Lindsay A. Farrer, Christine Van Broeckhoven, Michael C. O'Donovan, Anita L. Destefano, Lesley Jones, Jonathan L. Haines, Jean-Francois Deleuze, Michael J. Owen, Vilmundur Gudnason, Richard P. Mayeux, Valentina Escott-Price, Bruce M. Psaty, Agustin Ruiz, Alfredo Ramirez, Li-San Wang, Cornelia M. van Duijn, Peter A. Holmans, Sudha Seshadri, Julie Williams, Philippe Amouyel, Gerard D. Schellenberg, Jean-Charles Lambert, Margaret A. Pericak-Vance. BioRxiv.
Common and rare TBK1 variants in early-onset Alzheimer disease in a European cohort
Neurobiol Aging. 2018 Feb;62:245.e1-245.e7 F.I. 4.454. doi: 10.1016/j.neurobiolaging.2017.10.012. Epub 2017 Oct 25
Verheijen J1, van der Zee J1, Gijselinck I1, Van den Bossche T2, Dillen L1, Heeman B1, Gómez-Tortosa E3, Lladó A4, Sanchez-Valle R4, Graff C5, Pastor P6, Pastor MA7, Benussi L8, Ghidoni R8, Binetti G9, Clarimon J10, de Mendonça A11, Gelpi E12, Tsolaki M13, Diehl-Schmid J14, Nacmias B15, Almeida MR16, Borroni B17, Matej R18, Ruiz A19, Engelborghs S20, Vandenberghe R21, De Deyn PP20, Cruts M1, Van Broeckhoven C22, Sleegers K23; BELNEU Consortium; EU EOD Consortium.
CXCR4 involvement in neurodegenerative diseases
Transl Psychiatry. 2018 Apr 11;8(1):73. F.I. 4.691. doi: 10.1038/s41398-017-0049-7.
Bonham LW1, Karch CM2, Fan CC3, Tan C4, Geier EG1, Wang Y5, Wen N2, Broce IJ4, Li Y4, Barkovich MJ4, Ferrari R6, Hardy J6, Momeni P7, Höglinger G8,9, Müller U10, Hess CP4, Sugrue LP4, Dillon WP4, Schellenberg GD11, Miller BL1, Andreassen OA5, Dale AM3,12, Barkovich AJ4, Yokoyama JS1, Desikan RS13; International FTD-Genomics Consortium (IFGC); International Parkinson’s Disease Genetics Consortium (IPDGC); International Genomics of Alzheimer’s Project (IGAP).
Author Correction: Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS
Sci Rep. 2018 May 14;8(1):7789. F.I. 4.122. doi: 10.1038/s41598-018-21308-x.
Taskesen E1,2, Mishra A1, van der Sluis S1, Ferrari R3; International FTD-Genomics Consortium, Veldink JH4, van Es MA4, Smit AB5, Posthuma D1,2, Pijnenburg Y6.
Protein network analysis reveals selectively vulnerable regions and biological processes in FTD
Neurology Genetics. 2018 Oct 1;4(5):e266. doi: 10.1212/NXG.0000000000000266.
Bonham LW1, Steele NZR1, Karch CM1, Manzoni C1, Geier EG1, Wen N1, Ofori-Kuragu A1, Momeni P1, Hardy J1, Miller ZA1, Hess CP1, Lewis P1, Miller BL1, Seeley WW1, Baranzini SE1, Desikan RS1, Ferrari R1, Yokoyama JS1; International FTD-Genomics Consortium (IFGC).
Increased Albumin Oxidation in Cerebrospinal Fluid and Plasma from Alzheimer's Disease Patients
J Alzheimers Dis. 2018 May 16. F.I. 3.476. doi: 10.3233/JAD-180243
Costa M1, Horrillo R1, Ortiz AM1, Pérez A1, Mestre A1, Ruiz A2, Boada M2,3, Grancha S1.
Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease
N Engl J Med. 2018 Jan 25;378(4):321-330. F.I. 79.258. doi: 10.1056/NEJMoa1705971.
Honig LS, Vellas B, Woodward M, Boada M, Bullock R, Borrie M, Hager K, Andreasen N, Scarpini E, Liu-Seifert H, Case M, Dean RA, Hake A, Sundell K, Poole Hoffmann V, Carlson C, Khanna R, Mintun M, DeMattos R, Selzler KJ, Siemers E.
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
PLoS Med. 2018 Jan 9;15(1):e1002487. F.I. 11.675. doi: 10.1371/journal.pmed.1002487. eCollection 2018 Jan.
Broce I, Karch CM, Wen N, Fan CC, Wang Y, Hong Tan C, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J; International FTD-Genomics Consortium, Momeni P, Hess CP, Dillon WP, Miller ZA, Bonham LW, Rabinovici GD, Rosen HJ, Schellenberg GD, Franke A, Karlsen TH, Veldink JH, Ferrari R, Yokoyama JS, Miller BL, Andreassen OA, Dale AM, Desikan RS, Sugrue LP.
Longitudinal Neuroimaging Analysis in Mild-Moderate Alzheimer's Disease Patients Treated with Plasma Exchange with 5% Human Albumin
J Alzheimers Dis. 2018;61(1):321-332. F.I. 3.476. doi: 10.3233/JAD-170693.
Cuberas-Borrós G, Roca I, Boada M, Tárraga L, Hernández I, Buendia M, Rubio L, Torres G, Bittini Á, Guzmán-de-Villoria JA, Pujadas F, Torres M, Núñez L, Castell J, Páez A.
Safety, tolerability and immunogenicity of an active anti-Aβ40 vaccine (ABvac40) in patients with Alzheimer’s disease: a randomised, double-blind, placebo-controlled, phase I trial
Alzheimers Res Ther. 2018 Jan 29;10(1):12. F.I. 5.015. doi: 10.1186/s13195-018-0340-8
Ana-María Lacosta, María Pascual-Lucas, Pedro Pesini, Diego Casabona, Virginia Pérez-Grijalba, Iván Marcos-Campos, Leticia Sarasa, Jesus Canudas, Hassnae Badi, Inmaculada Monleón, Itziar San-José, Josep Munuera, Octavio Rodríguez-Gómez, Carla Abdelnour, Asunción Lafuente, Mar Buendía, Mercè Boada, Lluis Tárraga, Agustín Ruiz, Manuel Sarasa.
The Spanish version of Face-Name Associative Memory Exam (S-FNAME) performance is related to amyloid burden in Subjective Cognitive Decline
Sci Rep. 2018 Feb 28;8(1):3828. F.I. 4.122. doi: 10.1038/s41598-018-21644-y
Sanabria A, Alegret M, Rodriguez-Gomez O, Valero S, Sotolongo-Grau O, Monté-Rubio G, Abdelnour C, Espinosa A, Ortega G, Perez-Cordon A, Gailhajanet A, Hernandez I, Rosende-Roca M, Vargas L, Mauleon A, Sanchez D, Martin E, Rentz DM, Lomeña F, Ruiz A, Tarraga L, Boada M; FACEHBI study group.
Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporaldementia
Neurobiol Aging. 2018 Jun;66:181.e3-181.e10. F.I. 4.454. doi:10.1016/j.neurobiolaging.2018.02.011
Philtjens S, Van Mossevelde S, van der Zee J, Wauters E, Dillen L, Vandenbulcke M, Vandenberghe R, Ivanoiu A, Sieben A, Willems C7, Benussi L, Ghidoni R, Binetti G, Borroni B, Padovani A, Pastor P, Diez-Fairen M, Aguilar M, de Mendonça A, Miltenberger-Miltényi G, Hernández I, Boada M, Ruiz A, Nacmias B, Sorbi S, Almeida MR, Santana I, Clarimón J, Lleó A, Frisoni GB, Sanchez-Valle R, Lladó A, Gómez-Tortosa E, Gelpi E, Van den Broeck M, Peeters K, Cras P, De Deyn PP, Engelborghs S, Cruts M, Van Broeckhoven C; BELNEU Consortium; EU EOD Consortium25.
Patient Engagement: The Fundació ACE Framework for Improving Recruitment and Retention in Alzheimer's Disease Research
J Alzheimers Dis. 2018;62(3):1079-1090. F.I. 3.476. doi: 10.3233/JAD-170866
Boada M, Santos-Santos MA, Rodríguez-Gómez O, Alegret M, Cañabate P, Lafuente A, Abdelnour C, Buendía M, de Dios MJ, Morera A, Sanabria Á, Campo L, Ruiz A, Tárraga L.
The Role of Verb Fluency in the Detection of Early Cognitive Impairment in Alzheimer's Disease
J Alzheimers Dis. 2018;62(2):611-619. F.I. 3.476. doi: 10.3233/JAD-170826
Alegret M, Peretó M, Pérez A, Valero S, Espinosa A, Ortega G, Hernández I, Mauleón A, Rosende-Roca M, Vargas L, Rodríguez-Gómez O, Abdelnour C, Berthier ML, Bak TH, Ruíz A, Tárraga L, Boada M.
Los genes de la esquizofrenia que protegen del alzhéimer
Mente y cerebro, ISSN 1695-0887, Nº. 88, 2018, págs. 32-35
S Moreno, A Ruiz.
Altered topology of the functional speech production network in non-fluent/agrammatic variant of PPA
Cortex. 2018 Nov;108:252-264. F.I. 4.90 doi: 10.1016/j.cortex.2018.08.002
Mandelli ML, Welch AE, Vilaplana E, Watson C, Battistella G, Brown JA, Possin KL, Hubbard HI, Miller ZA, Henry ML, Marx GA, Santos-Santos MA, Bajorek LP, Fortea J, Boxer A, Rabinovici G, Lee S, Deleon J, Rosen HJ, Miller BL, Seeley WW, Gorno-Tempini ML.
Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia
Annals of Neurology. 2018 Nov;84(5):729-740. F.I. 10.24 doi: 10.1002/ana.25333.
Bergeron D, Gorno-Tempini ML, Rabinovici GD, Santos-Santos MA, Seeley W, Miller BL, Pijnenburg Y, Keulen MA, Groot C, van Berckel BNM, van der Flier WM, Scheltens P, Rohrer JD, Warren JD, Schott JM, Fox NC, Sanchez-Valle R, Grau-Rivera O, Gelpi E, Seelaar H, Papma JM, van Swieten JC, Hodges JR, Leyton CE, Piguet O, Rogalski EJ, Mesulam MM, Koric L, Nora K, Pariente J, Dickerson B, Mackenzie IR, Hsiung GR, Belliard S, Irwin DJ, Wolk DA, Grossman M, Jones M, Harris J, Mann D, Snowden JS, Chrem-Mendez P, Calandri IL, Amengual AA, Miguet-Alfonsi C, Magnin E, Magnani G, Santangelo R, Deramecourt V, Pasquier F, Mattsson N, Nilsson C, Hansson O, Keith J, Masellis M, Black SE, Matías-Guiu JA, Cabrera-Martin MN, Paquet C, Dumurgier J, Teichmann M, Sarazin M, Bottlaender M, Dubois B, Rowe CC, Villemagne VL, Vandenberghe R, Granadillo E, Teng E, Mendez M, Meyer PT, Frings L, Lleó A, Blesa R, Fortea J, Seo SW, Diehl-Schmid J, Grimmer T, Frederiksen KS, Sánchez-Juan P, Chételat G, Jansen W, Bouchard RW, Laforce RJ, Visser PJ, Ossenkoppele R.
Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia
JAMA Neurology. 2018 Mar 1;75(3):342-352. F.I. 11.46 doi: 10.1001/jamaneurol.2017.4309.
Santos-Santos MA, Rabinovici GD, Iaccarino L, Ayakta N, Tammewar G, Lobach I, Henry ML, Hubbard I, Mandelli ML, Spinelli E, Miller ZA, Pressman PS, O'Neil JP, Ghosh P, Lazaris A, Meyer M, Watson C, Yoon SJ, Rosen HJ, Grinberg L, Seeley WW, Miller BL, Jagust WJ, Gorno-Tempini ML.
Increased Albumin Oxidation in Cerebrospinal Fluid and Plasma from Alzheimer's Disease Patients
Journal of Alzheimer’s Disease. 2018 May 16. F.I. 3.476 doi: 10.3233/JAD-180243.
Costa M, Horrillo R, Ortiz AM, Pérez A, Mestre A, Ruiz A, Boada M, Grancha S.
Total impact factor: 257,42
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
Sonia Moreno-Grau, Itziar de Rojas, Isabel Hernández, Ines Quintela, Laura Montrreal, Montserrat Alegret, Begoña Olasagarre, Laura Madrid, Antonio González, Olalla Marona, Maitee Rosende-Roca, Ana Mauleon, Liliana Vargas, Asuncion Lafuente, Carla Abdelnour, Octavio Rodríguez-González, Silvia Gil, Miguel Ángel Santos-Santos, Ana Espinosa, Gemma Ortega, Ángela Sanabria, Alba Pérez-Cordón, Susana Ruiz, Nuria Aguilera, Juan Antonio Pineda, Juan Macias, Emilio Alarcón-Martín, Oscar Sotolongo-Grau, GR@ACE consortium, DEGESCO consortium, Alzheimer Disease Neuroimaging Initiative, Marta Marquié, Gemma Monte-Rubio, Sergi Valero, Jordi Clarimon, Maria Jesús Bullido, Guillermo Garcia-Ribas, Pau Pastor, Pascual Sánchez-Juan, Victoria Álvarez, Gerard Pinol-Ripoll, José María García-Alberca, José Luis Royo, Emilio Franco, Pablo Mir, Miguel Calero, Miguel Medina, Alberto Rabano, Jesus Ávila, Carmen Antúnez, Luis Miguel Real, Adelina Orellana, Ángel Carracedo, Maria Eugenia Sáez, Lluís Tàrraga, Mercè Boada, Agustín Ruiz.
Plasma exchange for Alzheimer's disease Management by Albumin Replacement (AMBAR) trial: Study design and progress
Boada M, López O, Núñez L, Szczepiorkowski ZM, Torres M, Grifols C, Páez A.
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Kunkle BW, Grenier-Boley B, Sims R Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roschupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh M, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller B, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y; Alzheimer Disease Genetics Consortium (ADGC),; European Alzheimer’s Disease Initiative (EADI),; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE),; Geneticand Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA13,20,212,304,305, Van Broeckhoven C15,16, C O'Donovan M5, DeStefano AL13,20, Jones L5,6, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA.
The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.
Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Buerger K, Levin J, Duering M, Dichgans M, Suárez-Calvet M, Haass C, Gordon BA, Lim YY, Masters CL, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Milz E, Moreno-Grau S, Teipel S, Grothe MJ, Kilimann I, Rossor M, Fox N, Laske C, Chhatwal J, Falkai P, Perneczky R, Lee JH, Spottke A, Boecker H, Brosseron F, Fliessbach K, Heneka MT, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Salloway S, Danek A, Hassenstab J, Yakushev I, Schofield PR, Morris JC, Bateman RJ, Ewers M.
Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease.
Egan MF, Kost J, Voss T, Mukai Y, Aisen PS, Cummings JL, Tariot PN, Vellas B, van Dyck CH, Boada M, Zhang Y, Li W, Furtek C, Mahoney E, Harper Mozley L, Mo Y, Sur C, Michelson D.
The MOPEAD project: Advancing patient engagement for the detection of “hidden” undiagnosed cases of Alzheimer's disease in the community.
Alzheimers Dement. 2019 Jun;15(6):828-839.
Octavio Rodríguez, Adrián Rodrigo, Fátima Iradier, Miguel A. Santos-Santos, Hans Hundemer, Andreea Ciudin, Lena Sannemann, Marissa Zwan, Bridget Glaysher, Anders Wimo, Jaka Bonn, Gunilla Johansson, Isabel Rodríguez, Montse Alegret, Dianne Govel, Susana Pinó, Paloma Trigueros, Miia Kivipelto, Brandy Mathews, Antonio Ciudad, Daniel Ferreira, Christophe Bintener, Miren Gurruchaga, Eric Westman, Mark Belger, Sergi Valero, Peggy Maguire, David Krivec, Milica Kramberger, Rafael Simó, Inmaculada Pérez Garro, Pieter Jelle Visserh, Annette Dumas, Jean Georges, Frank Jessen, Bengt Winblad, Craig Shering, Neil Stewart, Laura Campo, Mercè Boada on behalf of the MOPEAD Consortium.
Relevance of the interplay between amyloid and tau for cognitive impairment in early Alzheimer's disease.
Maarten Timmers, Ina Tesseur, Jennifer Bogert, Henrik Zetterberg, Kaj Blennow, Anne Börjesson-Hanson, Miquel Baquero, Mercè Boada, Christopher Randolph, Luc Tritsmans, LucVan Nueten, Sebastiaan Engelborgh, Johannes RolfStreffer.
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study.
Rongve A, Witoelar A, Ruiz A, Athanasiu L, Abdelnour C, Clarimon J, Heilmann-Heimbach S, Hernández I, Moreno-Grau S, de Rojas I, Morenas-Rodríguez E, Fladby T, Sando SB Bråthen G, Blanc F, Bousiges O, Lemstra AW, van Steenoven I, Londos E, Almdahl IS, Pålhaugen L, Eriksen JA, Djurovic S, Stordal E, Saltvedt I, Ulstein ID, Bettella F, Desikan RS, Idland AV, Toft M, Pihlstrøm L Snaedal, Tárraga L, Boada M, Lleó A, Stefánsson H, Stefánsson K, Ramírez A, Aarsland D, Andreassen OA.
A collection of four integration-free iPSC lines derived from diagnosed sporadic Alzheimer's disease patients with different APOE alleles.
Díaz-Guerra E, Moreno-Jiménez EP, de Rojas I, Rodríguez C, Rodríguez-Traver E, Arribas-González E, Orera M, Hernández I, Ruiz A, Vicario C.
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia.
Bonham LW, Steele NZR, Karch CM, Broce I, Geier EG, Wen NL, Momeni P, Hardy J, Miller ZA, Gorno-Tempini ML, Hess CP, Lewis P, Miller BL, Seeley WW, Manzoni C, Desikan RS, Baranzini SE, Ferrari R, Yokoyama JS; International FTD-Genomics Consortium (IFGC).
Genetic markers of lipid metabolism genes associated with low susceptibility to HCV infection.
Real LM, Macías J, Rivero-Juárez A, Téllez F, Merino D, Moreno-Grau S, Orellana A, Gómez-Salgado J, Sáez ME, Frías M, Corma-Gómez A, Merchante N, Ruiz A, Caruz A, Pineda JA; GEHEP 012 study group.
Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype.
Vermunt L, Sikkes SAM, van den Hout A, Handels R, Bos I, van der Flier WM, Kern S, Ousset PJ, Maruff P, Skoog I, Verhey FRJ, Freund-Levi Y, Tsolaki M, Wallin ÅK, Olde Rikkert M, Soininen H, Spiru L, Zetterberg H, Blennow K, Scheltens P, Muniz-Terrera G, Visser PJ; Alzheimer Disease Neuroimaging Initiative; AIBL Research Group; ICTUS/DSA study groups.
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
Van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez Rodríguez E; DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank); EADB (Alzheimer Disease European DNA biobank); IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium); IPDGC (The International Parkinson Disease Genomics Consortium); RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia); Netherlands Brain Bank (NBB), Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sørensen TIA, Heutink P, Sánchez-Juan P, Posthuma D; GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Clarimón J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H.
Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer's disease.
Siedlecki-Wullich D, Català-Solsona J, Fábregas C, Hernández I, Clarimon J, Lleó A, Boada M, Saura CA, Rodríguez-Álvarez J, Miñano-Molina AJ.
Letter Verbal Fluency in Spanish-, Basque-, and Catalan-Speaking Individuals: Does the Selection of the Letters Influence the Outcome?
Olabarrieta-Landa L, Benito-Sánchez I, Alegret M, Gailhajanet A, Landa Torre E, López-Mugartza JC, Arango-Lasprilla JC.
Visual impairment in aging and cognitive decline: experience in a Memory Clinic.
Marquié M, Castilla-Martí M, Valero S, Martínez J, Sánchez D, Hernández I, Rosende-Roca M, Vargas L, Mauleón A, Rodríguez-Gómez O, Abdelnour C, Gil S, Santos-Santos MA, Alegret M, Espinosa A, Ortega G, Pérez-Cordón A, Sanabria Á, Roberto N, Moreno-Grau S, de Rojas I, Simó R, Ciudin A, Hernández C, Orellana A, Monté-Rubio G, Benaque A, Ruiz A, Tárraga L, Boada M.
A genome-wide association study on low susceptibility to hepatitis C virus infection (GEHEP012 study).
Real LM, Fernández-Fuertes M, Sáez ME, Rivero-Juárez A, Frías M, Téllez F, Santos J, Merino D, Moreno-Grau S, Gómez-Salgado J, González-Serna A, Corma-Gómez A, Ruiz A, Macías J, Pineda JA.
Generation of an integration-free iPSC line, ICCSICi006-A, derived from a male Alzheimer's disease patient carrying the PSEN1-G206D mutation.
Díaz-Guerra E, Oria-Muriel MA, Moreno-Jiménez EP, de Rojas I, Rodríguez C, Rodríguez-Traver E, Orera M, Hernández I, Ruiz A, Vicario C.
An integration-free iPSC line, ICCSICi007-A, derived from a female Alzheimer's disease patient with the APOE-ε4/ε4 alleles.
Díaz-Guerra E, Rodríguez-Traver E, Moreno-Jiménez EP, de Rojas I, Rodríguez C, Orera M, Hernández I, Ruiz A, Vicario C.
A unique common ancestor introduced P301L mutation in MAPT gene in frontotemporal dementia patients from Barcelona (Baix Llobregat, Spain).
Palencia-Madrid L, Sánchez-Valle R, Fernández de Retana I, Borrego S, Grau-Rivera O, Reñé R, Hernández I, Almenar C, Rossi G, Caroppo P, Redaelli V, Le Ber I, Camuzat A, Brice A, Antonell A, Balasa M, Gelpi E, Lladó A, de Pancorbo MM.
CSF tau proteins correlate with an atypical clinical presentation in dementia with Lewy bodies.
Di Censo R, Abdelnour C, Blanc F, Bousiges O, Lemstra AW, van Steenoven I, Onofrj M, Aarsland D, Bonanni L; European DLB consortium.
Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer's disease.
M. E. Sáez A.González-Pérez, B. Hernández-Olasagarre, A. Beà, S. Moreno-Grau, I. de Rojas , G. Monté-Rubio, A.Orellana, S.Valero, J.X. Comella, D. Sanchís*& A. Ruiz.
Efficacy and Safety of Lanabecestat for Treatment of Early and Mild Alzheimer Disease: The AMARANTH and DAYBREAK-ALZ Randomized Clinical Trials.
Wessels AM, Tariot PN, Zimmer JA, Selzler KJ, Bragg SM, Andersen SW, Landry J, Krull JH, Downing AM, Willis BA, Shcherbinin S, Mullen J, Barker P, Schumi J, Shering C, Matthews BR, Stern RA, Vellas B, Cohen S, MacSweeney E, Boada M, Sims JR.
Plasma Aβ42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study.
Pérez-Grijalba V, Arbizu J, Romero J, Prieto E, Pesini P, Sarasa L, Guillen F, Monleón I, San-José I, Martínez-Lage P, Munuera J, Hernández I, Buendía M, Sotolongo-Grau O, Alegret M, Ruiz A, Tárraga L, Boada M, Sarasa M; AB255 Study Group.
The MAPT H1 Haplotype Is a Risk Factor for Alzheimer's Disease in APOE ε4 Non-carriers.
Sánchez-Juan P, Moreno S, de Rojas I, Hernández I, Valero S, Alegret M, Montrreal L, García González P, Lage C, López-García S, Rodríguez-Rodríguez E, Orellana A, Tárraga L, Boada M, Ruiz A.
Comparative Cognitive Effects of Choreographed Exercise and Multimodal Physical Therapy in Older Adults with Amnestic Mild Cognitive Impairment: Randomized Clinical Trial.
Bisbe M, Fuente-Vidal A, López E, Moreno M, Naya M, de Benetti C, Milà R, Bruna O, Boada M, Alegret M.
Cross-Sectional Characterization of Albumin Glycation State in Cerebrospinal Fluid and Plasma from Alzheimer’s Disease Patients.
Costa M, Mestre A, Horrillo R, Ortiz AM, Pérez A, Ruiz A, Boada M, Grancha S.
Evaluation of macular thickness and volume tested by optical coherence tomography as biomarkers for Alzheimer’s disease in a memory clinic.
Sánchez D, Castilla-Marti,M, Marquié M, Valero S, Moreno-Grau S, Rodríguez-Gómez O, Piferrer A, Martínez G, Martínez J, Rojas I, Hernández I, Abdelnour C, Rosende-Roca M, Vargas L, Mauleón A, Gil S, Alegret M, Ortega G, Espinosa A, Pérez-Cordón A, Sanabria Á, Roberto N, Ciudin A, Simó R, Hernández C, Tárraga L, Boada M, Ruiz A.
A computerized version of the Short Form of the Face-Name Associative Memory Exam (FACEmemory®) for the early detection of Alzheimer’s disease.
Alegret M, Muñoz N, Roberto N, Rentz DM, Valero S, Gil S, Marquié M, Hernández I, Riveros C, Sanabria A, Perez-Cordon A, Espinosa A, Ortega G, Mauleón A, Abdelnour C, Rosende-Roca M, Papp KV, Orellana A, Benaque A, Tárraga L, Ruiz A, Boada M.
Personality Factors and Subjective Cognitive Decline: The FACEHBI Cohort.
Muñoz N, Gomà-I-Freixanet M, Valero S, Rodríguez-Gómez O, Sanabria A, Pérez-Cordón A, Hernández I, Marquié M, Mir I, Martín E, Benaque A, Ruiz A, Tárraga L, Boada M, Alegret M.
Comparative Cognitive Effects of Choreographed Exercise and Multimodal Physical Therapy in Older Adults with Amnestic Mild Cognitive Impairment: Randomized Clinical Trial.
Bisbe M, Fuente-Vidal A, López E, Moreno M, Naya M, de Benetti C, Milà R, Bruna O, Boada M, Alegret M.
CCR 5 deficiency impairs CD 4+ T‐cell memory responses and antigenic sensitivity through increased ceramide synthesis.
Ana Martín‐Leal, Raquel Blanco, Josefina Casas, María E. Sáez, Elena Rodríguez‐Bovolenta, Itziar de Rojas, Carina Drechsler, Luis Miguel Real, Gemma Fabrias, Agustín Ruíz, Mario Castro, Wolfgang WA Schamel, Balbino Alarcón, Hisse M Santen and Santos Mañes.
Genetic architecture of neurodegenerative dementias.
Clarimon J, Moreno-Grau S, Cervera-Carles L, Dols-Icardo O, Sánchez-Juan P, Ruiz A.
Association Between Retinal Thickness and β-Amyloid Brain Accumulation in Individuals With Subjective Cognitive Decline: Fundació ACE Healthy Brain Initiative.
Marta Marquié, Sergi Valero, Miguel Castilla-Marti, Joan Martínez, Octavio Rodríguez-Gómez, Ángela Sanabria, Juan Pablo Tartari, Gemma C. Monté-Rubio, Oscar Sotolongo-Grau, Montserrat Alegret, Alba Pérez-Cordón, Natalia Roberto, Itziar de Rojas, Sonia Moreno-Grau, Laura Montrreal, Isabel Hernández, Maitee Rosende-Roca, Ana Mauleón, Liliana Vargas, Carla Abdelnour, Silvia Gil, Ester Esteban-De Antonio, Ana Espinosa, Gemma Ortega, Francisco Lomeña, Javier Pavia, Assumpta Vivas, Miguel Ángel Tejero, Marta Gómez-Chiari, Rafael Simó, Andreea Ciudin, Cristina Hernández, Adelina Orellana, Alba Benaque, Agustín Ruiz, Lluís Tárraga, Mercè Boada & on behalf of the FACEHBI study group.
Early Detection of Mild Cognitive Impairment (MCI) in Primary Care.
M.N. Sabbagh, M. Boada, S. Borson, M. Chilukuri, B. Dubois, J. Ingram, A. Iwata, A.P. Porsteinsson, K.L. Possin, G.D. Rabinovici, B. Vellas, S. Chao, A. Vergallo, H. Hampel.
Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting.
M.N. Sabbagh, M. Boada, S. Borson, P.M. Doraiswamy, B. Dubois, J. Ingram, A. Iwata, A.P. Porsteinsson, K.L. Possin, G.D. Rabinovici, B. Vellas, S. Chao, A. Vergallo, H. Hampel.
Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1.
Anna Sancho-Balsells, Veronica Brito, Belissa Fernández, Mónica Pardo, Marco Straccia, Silvia Ginés, Jordi Alberch, Isabel Hernández, Belén Arranz, Josep M. Canals and Albert Giralt.
CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers.
Shahzad Ahmad, Marta del Campo Milan, Oskar Hansson, Ayse Demirkan, Ruiz Agustin, Maria E. Sáez, Nikolaos Giagtzoglou, Alfredo Cabrera-Socorro, Margot H. M. Bakker, Alfredo Ramirez, Thomas Hankemeier, Erik Stomrud, Niklas Mattsson-Carlgren, Philip Scheltens, Wiesje M. van der Flier, M. Arfan Ikram, Anders Malarstig, Charlotte E. Teunissen, Najaf Amin & Cornelia M. van Duijn.
PLCG2 Protective Variant p.P522R Modulates Tau Pathology and Disease Progression in Patients With Mild Cognitive Impairment.
Luca Kleineidam, Vincent Chouraki, Tomasz Próchnicki, Sven J van der Lee, Laura Madrid Márquez, Holger Wagner-Thelen, Ilker Karaca, Leonie Weinhold, Steffen Wolfsgruber, Anne Boland, Pamela V Martino Adami, Piotr Lewczuk, Julius Popp, Frederic Brosseron, Iris E Jansen, Marc Hulsman, Johannes Kornhuber, Oliver Peters, Claudine Berr, Reinhard Heun, Lutz Frölich, Christophe Tzourio, Jean-François Dartigues, Michael Hüll, Ana Espinosa, Isabel Hernández, Itziar de Rojas, Adelina Orellana, Sergi Valero, Najada Stringa, Natasja M van Schoor, Martijn Huisman, Philip Scheltens, Alzheimer’s Disease Neuroimaging Initiative (ADNI); Eckart Rüther, Jean-Francois Deleuze, Jens Wiltfang, Lluis Tarraga, Matthias Schmid, Martin Scherer, Steffi Riedel-Heller, Michael T Heneka, Philippe Amouyel, Frank Jessen, Merce Boada, Wolfgang Maier, Anja Schneider, Antonio González-Pérez, Wiesje M van der Flier, Michael Wagner, Jean-Charles Lambert, Henne Holstege, Mª Eugenia Sáez, Eicke Latz, Agustin Ruiz, Alfredo Ramirez.
Autosomal Recessive Alzheimer’s disease (arAD): homozygosity mapping of genomic regions containing arAD loci.
Sonia Moreno-Grau, Maria Victoria Fernández, Itziar de Rojas, Isabel Hernández, Fabiana Farias, John P Budde, Inés Quintela, Laura Madrid, Antonio González-Perez, Laura Montrreal, Pablo Garcia-Gonzalez, Emilio Alarcón-Martín, Montserrat Alegret, Olalla Maroñas, Juan Antonio Pineda, Juan Macías, GR@ACE & DEGESCO consortia, Alzheimer’s Disease Neuroimaging Initiative, Marta Marquié, Sergi Valero, Alba Benaque, Jordi Clarimón, Maria Jesus Bullido, Guillermo García-Ribas, Pau Pástor, Pascual Sánchez Juan, Victoria Álvarez, Gerard Piñol-Ripoll, Jose María García-Alberca, José Luis Royo, Emilio Franco-Macías, Pablo Mir, Miguel Calero, Miguel Medina, Alberto Rábano, Jesús Ávila, Carmen Antúnez, Luis Miguel Real, Adelina Orellana, Ángel Carracedo, María Eugenia Sáez, Lluis Tárraga, Mercè Boada, Carlos Cruchaga, Agustín Ruiz.
Dementia Care in Times of COVID-19: Experience at Fundació ACE in Barcelona, Spain.
Benaque, Alba; Gurruchaga, Miren Jone; Abdelnour, Carla; Hernández, Isabel; Cañabate, Pilar; Alegret, Montserrat; Rodríguez, Isabel; Rosende-Roca, Maitee; Tartari, Juan Pablo; Esteban, Ester; López, Rogelio; Gil, Silvia; Vargas, Liliana; Mauleón, Ana; Espinosa, Ana; Ortega, Gemma; Sanabria, Angela; Pérez, Alba; Alarcón, Emilio; González-Pérez, Antonio; Marquié, Marta; Valero, Sergi; Tárraga, Lluís; Ruiz, Agustín; Boada, Mercè; for the Research Center and Memory Clinic, Fundació ACE.
Rationale for Early Diagnosis of Mild Cognitive Impairment (MCI) Supported by Emerging Digital Technologies.
M N Sabbagh, M Boada, S Borson, M Chilukuri, P M Doraiswamy, B Dubois, J Ingram, A Iwata, A P Porsteinsson, K L Possin, G D Rabinovici, B Vellas, S Chao, A Vergallo, H Hampel.
The combined effect of amyloid-β and tau biomarkers on brain atrophy in dementia with Lewy bodies.
Carla Abdelnour, Daniel Ferreira, Ketil Oppedal, Lena Cavallin, Olivier Bousiges, Lars Olof Wahlund, Jakub Hort, Zuzana Nedelska, Alessandro Padovani. Andrea Pilotto, Laura Bonanni, Milica G. Kramberger, Mercè Boada, Eric Westman, Javier Pagonabarraga, Jaime Kulisevsky, Frédéric Blanc, Dag Aarsland.
A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study.
Mercè Boada, Oscar L. López, Javier Olazarán, Laura Núñez, Michael Pfeffer, María Paricio, Jesús Lorites, Gerard Piñol‐Ripoll, José E. Gámez, Fernando Anaya, Dobri Kiprov, José Lima, Carlota Grifols, Mireia Torres, Montserrat Costa, Jordi Bozzo, Zbigniew M. Szczepiorkowski, Suzanne Hendrix, Antonio Páez.
Clinical Applicability of the Specific Risk Score of Dementia in Type 2 Diabetes in the Identification of Patients with Early Cognitive Impairment: Results of the MOPEAD Study in Spain.
Angel Michael Ortiz Zúñiga, Rafael Simó, Octavio Rodriguez-Gómez, Cristina Hernández, Adrian Rodrigo, Laura Jamilis, Laura Campo, Montserrat Alegret, Mercè Boada, Andreea Ciudin.
C9orf72, AAO and ancestry help discriminating behavioural from language variants in FTLD cohorts.
Beatrice Costa, Claudia Manzoni, Manuel Bernal-Quiros, Demis A Kia, Miquel Aguilar, Ignacio Alvarez, Victoria Alvarez, Ole Andreassen, Maria Anfossi, Silvia Bagnoli, Luisa Benussi, Livia Bernardi, Giuliano Binetti, Daniel Blackburn, Mercè Boada, Barbara Borroni, Lucy Bowns, Geir Brathen, Amalia C Bruni, Huei-Hsin Chiang, Jordi Clarimon, Shuna Colville, Maria E Conidi, Tom E Cope, Carlos Cruchaga, Chiara Cupidi, Maria Elena Di Battista, Janine Diehl-Schmid, Monica Diez-Fairen, Oriol Dols-Icardo, Elisabetta Durante, Dusan Flisar, Francesca Frangipane, Daniela Galimberti, Maura Gallo, Maurizio Gallucci, Roberta Ghidoni, Caroline Graff, Jordan H Grafman, Murray Grossman, John Hardy, Isabel Hernández, Guy JT Holloway, Edward D Huey, Ignacio Illán-Gala, Anna Karydas, Behzad Khoshnood, Milica G Kramberger, Mark Kristiansen, Patrick A Lewis, Alberto Lleó, Gaganjit K Madhan, Raffaele Maletta, Ales Maver, Manuel Menendez-Gonzalez, Graziella Milan, Bruce Miller, Merel O Mol, Parastoo Momeni, Sonia Moreno-Grau, Chris M Morris, Benedetta Nacmias, Christer Nilsson, Valeria Novelli, Linn Öijerstedt, Alessandro Padovani, Suvankar Pla, Yasmin Panchbhaya, Pau Pastor, Borut Peterlin, Irene Piaceri, Stuart Pickering-Brown, Yolande AL Pijnenburg, Annibale A Puca, Innocenzo Rainero, Antonella Rendina, Anna MT Richardson, Ekaterina Rogaeva, Boris Rogelj, Sara Rollinson, Giacomina Rossi, Carola Rossmeier, James B Rowe, Elisa Rubino, Agustin Ruiz, Raquel Sanchez-Valle, Sigrid B Sando, Alexander F Santillo, Jennifer Saxon, Elio Scarpini, Maria Serpente, Nicoletta Smirne, Sandro Sorbi, EunRan Suh, Fabrizio Tagliavini, Jennifer C Thompson, JOhn Q Trojanowski, Vivianna M Van Deerlin, Julie Van der Zee, Christine Van Broeckhoven, Jeroen van Rooij, John C Van Swieten, Arianna Veronesi, Emilia Vitale, Maria L Waldö, Cathy Woodward, Jennifer Yokoyama, Valentina Escott-Price, James M Polke, Raffaele Ferrari, for the International FTD-Genetics Consortium (IFGC).
Managing Clinical Trials for Alzheimer's Disease During the COVID-19 Crisis: Experience at Fundació ACE in Barcelona, Spain.
Carla Abdelnour, Ester Esteban de Antonio, Alba Pérez-Cordón, Asunción Lafuente, Mar Buendía, Ana Pancho, Sara Jofresa, Nuria Aguilera, Marta Ibarria, Rosario Cuevas, Laia Cañada, Anna Calvet, Susana Diego, Antonio González-Pérez, Adela Orellana, Laura Montrreal, Laura de Jorge, Marta Marquié, Alba Benaque, Miren Gurruchaga, Lluís Tárraga, Agustín Ruiz, Mercè Boada, Research Center and Memory Clinic, Fundació ACE
Cognitive and neuropsychiatric manifestations of COVID-19 and effects on elderly individuals with dementia.
Silvia Alonso-Lana, Marta Marquié, Agustín Ruiz and Mercè Boada
Amyloid-β and tau biomarkers and clinical phenotype in dementia with Lewy bodies.
Daniel Ferreira, Scott A. Przybelski, Timothy G. Lesnick, Afina W. Lemstra, Elisabet Londos, Frederic Blanc, Zuzana Nedelska, Christopher G. Schwarz, Jonathan Graff-Radford, Matthew L. Senjem, Julie A. Fields, David S. Knopman, Rodolfo Savica, Tanis J. Ferman, Neill R. Graff-Radford, Val J. Lowe, Clifford R. Jack, Ronald C. Petersen, Brit Mollenhauer, Sara Garcia-Ptacek, Carla Abdelnour, Jakub Hort, Laura Bonanni, Ketil Oppedal, Milica G. Kramberger, Bradley F. Boeve, Dag Aarsland, Eric Westman, Kejal Kantarci.
Subtle executive deficits are associated with higher brain amyloid burden and lower cortical volume in subjective cognitive decline: the FACEHBI cohort.
Alba Pérez-Cordón, Gemma Monté-Rubio, Angela Sanabria, Octavio Rodriguez-Gómez, Sergi Valero, Carla Abdelnour, Marta Marquié, Ana Espinosa, Gemma Ortega, Isabel Hernandez, Maitee Rosende-Roca, Liliana Vargas, Ana Mauleón, Silvia Gil, Juan Pablo Tartari, Francisco Lomeña, Francisco Campos, Assumpta Vivas, Marta Gomez-Chiari, Alba Benaque, Agustin Ruiz, Luis Tárraga, Mercè Boada, Montserrat Alegret & FACEHBI Group.
Heterozygous APOE Christchurch in familial Alzheimer's disease without mutations in other Mendelian genes.
Isabel Hernández, Ellen Gelpi, Laura Molina-Porcel, Sara Bernal, Benjamín Rodríguez-Santiago, Oriol Dols-Icardo, Agustín Ruiz, Daniel Alcolea, Mercè Boada, Alberto Lleó, Jordi Clarimón
