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AMBAR has 2 phases. It begins with an intensive phase, that lasts 6 weeks, followed by the maintenance phase, the duration of which will be established according to medical criteria. Follow-up visits with the neurologist are done every 3 months.
During the intensive phase, a complete plasma exchange is made per week. During it, all the blood is circulated through the separation machine and the withdrawn plasma is replaced by a 5% concentration albumin solution. The procedure takes approximately 2 and a half hours.
During the maintenance phase, a partial plasma exchange is performed once a month. In this case, the amount of plasma withdrawn is much less, similar to a blood donation, and it is replaced with a 20% albumin solution. In this case, the procedure lasts 2 hours.
Before the procedure, the person will have a blood test to verify that they are suitable for the session. During the procedure, the person will lie down comfortably in a reclining chair and a specialized healthcare professional will connect them to the plasma exchange device through a vein in the arm. During the entire procedure you will be under constant medical supervision. All medical equipment that comes into contact with blood is sterile and for single use. A member of the AMBAR Center Barcelona team will follow up within 24 hours.
People who desire to opt for the procedure must make an informative visit with a neurologist and undergo additional tests if the professional so request. If suitable for procedure is confirmed, the first phase of AMBAR begins.
The plasma therapeutic exchange is a very safe procedure for everyone and, after the treatment protocol, patients will be able to return to their normal daily activities. Only, as a precaution, they should limit vigorous activity for 24 hours after the procedure. In addition, a member of AMBAR Center Barcelona team will follow up on your condition by phone the following day.
Albumin is the most abundant protein in the blood and, among other functions, serves to carry substances through the bloodstream. It also transports the beta-amyloid protein, which accumulates in the brains of people with Alzheimer’s creating plaques that destroy neurons. Therefore, if we periodically extract this plasma, beta-amyloid could be eliminated, restricting the impact of Alzheimer’s on the cognitive functions of the person.
The plasma exchange is a medical procedure used for decades in the treatment of multiple neurological diseases, and other disorders, such as renal disorders or Crohn’s disease.
It lies in extracting the patient’s blood through a medical device that separates its different components: plasma (liquid part of the blood) and blood cells (red blood cells, white blood cells and platelets). The extracted plasma is replaced by albumin, which is administered to the patient along with blood cells.